Evidence map›Paper›PMID 34622441›Full record

SynthesisActa anaesthesiologica Scandinavica2022

Rapid Evaluation of Coronavirus Illness Severity (RECOILS) in intensive care: Development and validation of a prognostic tool for in-hospital mortality.

Drago Plečko, Nicolas Bennett, Johan Mårtensson, Tariq A Dam, Robert Entjes, Thijs C D Rettig, Dave A Dongelmans, Age D Boelens, Sander Rigter, Stefaan H A Hendriks and 37 more

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Acta anaesthesiologica Scandinavica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Blood urea nitrogen and creatinine in in-hospital cardiac arrest patients.Journal of the Chinese Medical Association : JCMA · 2023
    Article
  6. Observational
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

47 authors at 20 institutions in 5 countries.

Drago PlečkoDepartment of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Amsterdam, The Netherlands.ORCID 0000-0002-5433-196X
Nicolas BennettDepartment of Mathematics, Seminar for Statistics, ETH Zürich, Zurich, Switzerland.
Johan MårtenssonDepartment of Physiology and Pharmacology, Section of Anaesthesia and Intensive Care, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-8739-7896
Tariq A DamDepartment of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Amsterdam, The Netherlands.
Robert EntjesDepartment of Intensive Care, Admiraal De Ruyter Ziekenhuis, Goes, The Netherlands.
Thijs C D RettigDepartment of Intensive Care, Amphia Ziekenhuis, Breda, The Netherlands.
Dave A DongelmansDepartment of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Amsterdam, The Netherlands.
Age D BoelensAntonius Ziekenhuis Sneek, Sneek, The Netherlands.
Sander RigterDepartment of Anesthesiology and Intensive Care, St. Antonius Hospital, Nieuwegein, The Netherlands.
Stefaan H A HendriksIntensive Care, Albert Schweitzerziekenhuis, Dordrecht, The Netherlands.
Remko de JongIntensive Care, Bovenij Ziekenhuis, Amsterdam, The Netherlands.
Marlijn J A KampsIntensive Care, Catharina Ziekenhuis Eindhoven, Eindhoven, The Netherlands.
Marco PetersIntensive Care, Canisius Wilhelmina Ziekenhuis, Nijmegen, The Netherlands.
Attila KarakusDepartment of Intensive Care, Diakonessenhuis Hospital, Utrecht, The Netherlands.
Diederik GommersDepartment of Intensive Care, Erasmus Medical Center, Rotterdam, The Netherlands.
Dharmanand RamnarainIntensive Care, ETZ Tilburg, Tilburg, The Netherlands.
Evert-Jan WilsDepartment of Intensive Care, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands.
Sefanja AchterbergICU, Haaglanden Medisch Centrum, Den Haag, The Netherlands.
Ralph NowitzkyIntensive Care, HagaZiekenhuis, Den Haag, The Netherlands.
Walter van den TempelDepartment of Intensive Care, Ikazia Ziekenhuis Rotterdam, Rotterdam, The Netherlands.
Cornelis P C de JagerDepartment of Intensive Care, Jeroen Bosch Ziekenhuis, Den Bosch, The Netherlands.
Fleur G C A NooteboomIntensive Care, Laurentius Ziekenhuis, Roermond, The Netherlands.
Evelien OostdijkICU, Maasstad Ziekenhuis Rotterdam, Rotterdam, The Netherlands.
Peter KoetsierIntensive Care, Medisch Centrum Leeuwarden, Leeuwarden, The Netherlands.
Alexander D CornetDepartment of Intensive Care, Medisch Spectrum Twente, Enschede, The Netherlands.
Auke C ReidingaICU, SEH, BWC, Martiniziekenhuis, Groningen, The Netherlands.
Wouter de RuijterDepartment of Intensive Care Medicine, Northwest Clinics, Alkmaar, The Netherlands.
Rob J BosmanICU, OLVG, Amsterdam, The Netherlands.
Tim FrenzelDepartment of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Louise C Urlings-StropIntensive Care, Reinier de Graaf Gasthuis, Delft, The Netherlands.
Paul de JongDepartment of Anesthesia and Intensive Care, Slingeland Ziekenhuis, Doetinchem, The Netherlands.
Ellen G M SmitIntensive Care, Spaarne Gasthuis, Haarlem en Hoofddorp, The Netherlands.
Olaf L CremerIntensive Care, UMC Utrecht, Utrecht, The Netherlands.
D Jannet Mehagnoul-SchipperIntensive Care, VieCuri Medisch Centrum, Venlo, The Netherlands.
Harald J FaberICU, WZA, Assen, The Netherlands.
Judith LensICU, ICU, IJsselland Ziekenhuis, Capelle aan den IJssel, The Netherlands.
Gert B BrunnekreefDepartment of Intensive Care, Ziekenhuisgroep Twente, Almelo, The Netherlands.
Barbara Festen-SpanjerIntensive Care, Ziekenhuis Gelderse Vallei, Ede, The Netherlands.
Tom DormansIntensive care, Zuyderland MC, Heerlen, The Netherlands.
Daan P de BruinPacmed, Amsterdam, Amsterdam, The Netherlands.
Robbert C A LalisangPacmed, Amsterdam, Amsterdam, The Netherlands.
Sebastiaan J J VonkPacmed, Amsterdam, Amsterdam, The Netherlands.
Martin E HaanDepartment of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Amsterdam, The Netherlands.
Lucas M FleurenDepartment of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Amsterdam, The Netherlands.
Patrick J ThoralDepartment of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Amsterdam, The Netherlands.
Paul W G ElbersDepartment of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam UMC, Amsterdam, The Netherlands.
Rinaldo BellomoAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventative Medicine, Monash University, Melbourne, Australia.
Amsterdam University Medical Centers · NLAmsterdam University College · NLETH Zurich · CHRadboud University Nijmegen · NLSt. Antonius Ziekenhuis · NLAdmiraal De Ruyter Ziekenhuis · NLAlbert Schweitzer Ziekenhuis · NLAmphia Ziekenhuis · NLAsser Institute · NLCanisius-Wilhelmina Ziekenhuis · NLDiakonessenhuis hospital · NLErasmus MC · NLHaga Hospital · NLIJsselland Ziekenhuis · NLIkazia Ziekenhuis · NLJeroen Bosch Ziekenhuis · NLKarolinska University Hospital · SELaurentius Ziekenhuis · NLMaasstad Ziekenhuis · NLMartini Ziekenhuis · NL

Funding

Personalized Health and Related Technologies (PHRT) #2017-110
6 · The paper itself

Abstract

backgroundThe prediction of in-hospital mortality for ICU patients with COVID-19 is fundamental to treatment and resource allocation. The main purpose was to develop an easily implemented score for such prediction.

methodsThis was an observational, multicenter, development, and validation study on a national critical care dataset of COVID-19 patients. A systematic literature review was performed to determine variables possibly important for COVID-19 mortality prediction. Using a logistic multivariable model with a LASSO penalty, we developed the Rapid Evaluation of Coronavirus Illness Severity (RECOILS) score and compared its performance against published scores.

resultsOur development (validation) cohort consisted of 1480 (937) adult patients from 14 (11) Dutch ICUs admitted between March 2020 and April 2021. Median age was 65 (65) years, 31% (26%) died in hospital, 74% (72%) were males, average length of ICU stay was 7.83 (10.25) days and average length of hospital stay was 15.90 (19.92) days. Age, platelets, PaO2/FiO2 ratio, pH, blood urea nitrogen, temperature, PaCO2, Glasgow Coma Scale (GCS) score measured within +/-24 h of ICU admission were used to develop the score. The AUROC of RECOILS score was 0.75 (CI 0.71-0.78) which was higher than that of any previously reported predictive scores (0.68 [CI 0.64-0.71], 0.61 [CI 0.58-0.66], 0.67 [CI 0.63-0.70], 0.70 [CI 0.67-0.74] for ISARIC 4C Mortality Score, SOFA, SAPS-III, and age, respectively).

conclusionsUsing a large dataset from multiple Dutch ICUs, we developed a predictive score for mortality of COVID-19 patients admitted to ICU, which outperformed other predictive scores reported so far.

Indexed as

COVID-19AdultAgedCritical CareHospital MortalityHumansIntensive Care UnitsMaleMulticenter Studies as TopicObservational Studies as TopicPatient AcuityPrognosisRetrospective StudiesSARS-CoV-2corona virusCOVID-19intensive caremechanical ventilationrespiratory failure

Identifiers

PMID34622441
PMCPMC8652966
OpenAlexW3203985152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.