Evidence map›Paper›PMID 34622436›Full record

SynthesisCardiology journal2023

Meta-analysis of chest compression-only versus conventional cardiopulmonary resuscitation by bystanders for adult with out-of-hospital cardiac arrest.

Karol Bielski, Jacek Smereka, Jaroslaw Chmielewski, Michal Pruc, Francesco Chirico, Aleksandra Gasecka, Nataliia Litvinova, Milosz J Jaguszewski, Grazyna Nowak-Starz, Zubaid Rafique and 2 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Cardiology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 5 countries.

Karol BielskiInstitute of Outcomes Research, Polonia Academy, Czestochowa, Poland.ORCID 0000-0002-2428-0671
Jacek SmerekaPolish Society of Disaster Medicine, Warsaw, Poland.ORCID 0000-0002-1427-4796
Jaroslaw ChmielewskiCollege of Rehabiliation, Warsaw, Poland.ORCID 0000-0003-2606-1656
Michal PrucPolish Society of Disaster Medicine, Warsaw, Poland.
Francesco ChiricoPostgraduate School of Occupational Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0002-2140-9732
Aleksandra GaseckaLaboratory of Experimental Clinical Chemistry, Amsterdam University Medical Center, Amsterdam, the Netherlands.ORCID 0000-0002-8737-4368
Nataliia LitvinovaEuropean Medical School, International European University, Kiev, Ukraine.ORCID 0000-0001-5083-7587
Milosz J Jaguszewski1st Department of Cardiology, Medical University of Gdansk, Gdansk, Poland.ORCID 0000-0001-8079-7328
Grazyna Nowak-StarzCollegium Medicum Institute of Health Sciences, Kochanowski University, Kielce, Poland.ORCID 0000-0003-2032-7484
Zubaid RafiqueHenry JN Taub Department of Emergency Medicine, Baylor College of Medicine Houston, TX, United States.ORCID 0000-0001-7804-2129
Frank W PeacockHenry JN Taub Department of Emergency Medicine, Baylor College of Medicine Houston, TX, United States.ORCID 0000-0002-4176-5988
Lukasz SzarpakMaria Sklodowska-Curie Medical Academy, Warsaw, Poland. lukasz.szarpak@gmail.com.ORCID 0000-0002-0973-5455
Baylor College of Medicine · USPolonia University · PLAmsterdam University Medical Centers · NLGdańsk Medical University · PLInternational European UniversityJan Kochanowski University · PLKrakowskie Centrum Rehabilitacji · PLMedical University of Białystok · PLMinistry of Interior · ITWroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccording to the guidelines of cardiopulmonary resuscitation (CPR) conducted by bystanders, two methods of CPR are feasible: standard CPR (sCPR) with mouth-to-mouth ventilations and continuous chest compression-only CPR (CCC) without rescue breathing. The goal herein, was to evaluate the effect of sCPR (30:2) and CCC on resuscitation outcomes in patients with out-of-hospital cardiac arrest (OHCA) patients.

methodsThis study was a systematic review and meta-analysis. Using standardized criteria, Pub- Med, Web of Science, Scopus, EMBASE and Cochrane Collaboration were searched for trials assessing the effect of sCPR vs. CCC on resuscitation outcomes after adult OHCA. Random-effects model meta-analysis was applied to calculate the mean deviation (MD), odds ratio (OR) and 95% confidence interval (CI).

resultsOverall, 3 randomized controlled trials and 12 non-randomized trials met the inclusion criteria. Survival to hospital discharge with sCPR was 10.2% compared to 9.3% in the CCC group (OR = 1.04; 95% CI: 0.93-1.16; p = 0.46). Survival to hospital discharge with good neurological outcome measured with the cerebral performance category (CPC 1 or 2) was 6.5% for sCPR vs. 5.8% for CCC (OR = 1.00; 95% CI: 0.84-1.20; p = 0.98). Prehospital return of spontaneous circulation (ROSC) in sCPR and CCC groups was 15.9% and 14.8%, respectively (OR = 1.13; 95% CI: 0.91-1.39; p = 0.26). Survival to hospital admission with ROSC occurred in 29.5% of the sCPR group compared to 28.4% in CCC group (OR = 1.20; 95% CI: 0.89-1.63; p = 0.24).

conclusionsThis systematic review and meta-analysis concluded that there were no significant differences in the resuscitation outcomes between the use of standard cardiopulmonary resuscitation and chest compression only.

Indexed as

Cardiopulmonary ResuscitationOut-of-Hospital Cardiac ArrestAdultHospitalizationHumansPatient DischargeReturn of Spontaneous Circulationcardiopulmonary resuscitationchest compressioncontinuous compressionsout-of-hospital cardiac arrest

Identifiers

PMID34622436
PMCPMC10508072
OpenAlexW3204354909

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.