Evidence map›Paper›PMID 34622425›Full record

ArticleMolecular imaging and biology2022

PET/MRI and PET/CT Radiomics in Primary Cervical Cancer: A Pilot Study on the Correlation of Pelvic PET, MRI, and CT Derived Image Features.

Shadi A Esfahani, Angel Torrado-Carvajal, Barbara Juarez Amorim, David Groshar, Liran Domachevsky, Hanna Bernstine, Dan Stein, Debra Gervais, Onofrio A Catalano

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In one paragraph

Article in Molecular imaging and biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  5. The use of PET/MRI in radiotherapy.Insights into imaging · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Shadi A Esfahani *Department of Radiology, Division of Abdominal Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Angel Torrado-Carvajal *Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital Boston and Harvard Medical School, Boston, MA, USA.
Barbara Juarez AmorimDivision of Nuclear Medicine, State University of Campinas (UNICAMP), Campinas, Brazil.
David GrosharSackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Liran DomachevskySackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Hanna BernstineSackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Dan SteinDepartment of Nuclear Medicine and Radiology, Assuta Medical Centers, Tel-Aviv, Israel.
Debra GervaisDepartment of Radiology, Division of Abdominal Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Onofrio A CatalanoDepartment of Radiology, Division of Abdominal Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. ocatalano@mgh.harvard.edu.
Assuta Medical Center · ILBoston University · USAthinoula A. Martinos Center for Biomedical Imaging · USMassachusetts General Hospital · USTel Aviv University · ILUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the correlation of radiomic features in pelvic [2-deoxy-2-18F]fluoro-D-glucose positron emission tomography/magnetic resonance imaging and computed tomography ([ PROCEDURES: Nineteen patients with histologically confirmed primary squamous cell carcinoma of the cervix underwent same-day [

resultsFor a total of 101 extracted features, 1104/5050 pairs of features showed a significant correlation (ρ ≥ 0.70, p < 0.05). There was a strong correlation between 190/484 PET pairs of features from PET/MRI and PET/CT, 91/418 pairs of CT and PET from PET/CT, 79/418 pairs of T2 and PET from PET/MRI, and 50/418 pairs of ADC and PET from PET/MRI. Significant difference was seen between eight features in local and metastatic tumors including MTV, TLG, and entropy on PET from PET/CT; MTV and TLG on PET from PET/MRI; compactness and entropy on T2; and entropy on ADC images.

conclusionsWe demonstrated strong correlation of many extracted radiomic features between PET/MRI and PET/CT. Eight radiomic features calculated on PET/CT and PET/MRI were significantly different between local and metastatic CCa. This study paves the way for future studies to evaluate the diagnostic and predictive potential of radiomics that could guide clinicians toward personalized patients care.

Indexed as

Positron Emission Tomography Computed TomographyUterine Cervical NeoplasmsFemaleFluorodeoxyglucose F18HumansMagnetic Resonance ImagingPilot ProjectsPositron-Emission TomographyRadiopharmaceuticalsRetrospective StudiesTomography, X-Ray ComputedTumor BurdenFluorodeoxyglucose F18Radiopharmaceuticals[2-deoxy-2-18F]fluoro-D-glucoseCervical cancerPET/CTPET/MRPET/MRIRadiomicsSquamous cell carcinoma

Identifiers

PMID34622425
OpenAlexW3203943083

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.