ArticleCerebral cortex (New York, N.Y. : 1991)2022
Reward-Based Decision-Making Engages Distinct Modes of Cross-Frequency Coupling.
Article in Cerebral cortex (New York, N.Y. : 1991), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 18 citations in OpenAlex.
- Reduction in Left Frontal Alpha Oscillations by Transcranial Alternating Current Stimulation in Major Depressive Disorder Is Context Dependent in a Randomized Clinical Trial.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Trial
- Modulation of prefrontal theta oscillations slows social cognition.Cognitive, affective & behavioral neuroscience · 2026Article
- Advancing Stroke Recovery Through Operant Conditioning of Corticomuscular Coherence.Restorative neurology and neuroscience · 2026Review
- Causal Evidence for Prefrontal-Motor Coupling in Reward-Responsive Goal-Directed Behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Prefrontal Hierarchical Control of Corticomuscular Coherence in Stroke.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- Augmenting single-session behavioral activation for depression with delta-beta tACS: Preliminary investigation of a double-blind placebo-controlled randomized pilot clinical trial.Journal of mood and anxiety disorders · 2025Article
- Substance use disorder severity is associated with sensitivity to effort-related decision-making constraints.Psychopharmacology · 2025Article
- Prefrontal Internal Event-Driven Analysis of Dynamical Electroencephalographic Biomarkers in Depression During Emotional Auditory Task.CNS neuroscience & therapeutics · 2025Article
- Cortical and subcortical activities during food rewards versus social interaction in rats.Scientific reports · 2025Article
- Evaluation of Theta EEG Neurofeedback Procedure for Cognitive Training Using Simultaneous fMRI in Counterbalanced Active-Sham Study Design.Human brain mapping · 2025Article
- What can neurofeedback and transcranial alternating current stimulation reveal about cross-frequency coupling?Frontiers in neuroscience · 2025Article
- Neural correlates underlying state anxiety alterations following sleep deprivation: insights from frontal alpha asymmetry and phase-amplitude coupling.Frontiers in psychology · 2025Article
- Cross-Frequency Coupling as a Biomarker for Early Stroke Recovery.Neurorehabilitation and neural repair · 2024Article
- Hierarchical consciousness: the Nested Observer Windows model.Neuroscience of consciousness · 2024Article
- Mental Activity as the Bridge between Neural Biomarkers and Symptoms of Psychiatric Illness.Clinical EEG and neuroscience · 2023Article
- Article
- Amplitude modulating frequency overrides carrier frequency in tACS-induced phosphene percept.Human brain mapping · 2023Article
- Neurocognitive, physiological, and biophysical effects of transcranial alternating current stimulation.Trends in cognitive sciences · 2023Review
- Cross-Frequency Coupling and Intelligent Neuromodulation.Cyborg and bionic systems (Washington, D.C.) · 2023Review
- Comparison of event-related modulation index and traditional methods for evaluating phase-amplitude coupling using simulated brain signals.Biological cybernetics · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Prefrontal cortex exerts control over sensory and motor systems via cross-frequency coupling. However, it is unknown whether these signals play a role in reward-based decision-making and whether such dynamic network configuration is altered in a major depressive episode. We recruited men and women with and without depression to perform a streamlined version of the Expenditure of Effort for Reward Task during recording of electroencephalography. Goal-directed behavior was quantified as willingness to exert physical effort to obtain reward, and reward-evaluation was the degree to which the decision to exert effort was modulated by incentive level. We found that the amplitude of frontal-midline theta oscillations was greatest in participants with the greatest reward-evaluation. Furthermore, coupling between frontal theta phase and parieto-occipital gamma amplitude was positively correlated with reward-evaluation. In addition, goal-directed behavior was positively correlated with coupling between frontal delta phase to motor beta amplitude. Finally, we performed a factor analysis to derive 2 symptom dimensions and found that mood symptoms positively tracked with reward-evaluation and motivation symptoms negatively tracked with goal-directed behavior. Altogether, these results provide evidence that 2 aspects of reward-based decision-making are instantiated by different modes of prefrontal top-down control and are modulated in different symptom dimensions of depression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.