Evidence map›Paper›PMID 34622235›Full record

ArticleCell reports. Medicine2021

Identification of

Atsushi Ueda, Shoji Shinkai, Hirotsugu Shiroma, Yu Taniguchi, Sayaka Tsuchida, Takahiro Kariya, Tomohiro Kawahara, Yodai Kobayashi, Noriyuki Kohda, Kazunari Ushida and 2 more

Abstract read
In one paragraph

Article in Cell reports. Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Effect of PostbioticNutrients · 2024
    Trial
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Atsushi UedaSchool of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan.
Shoji ShinkaiResearch Team for Social Participation and Community Health, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Hirotsugu ShiromaSchool of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan.
Yu TaniguchiResearch Team for Social Participation and Community Health, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Sayaka TsuchidaCollege of Bioscience and Biotechnology, Chubu University, Aichi, Japan.
Takahiro KariyaOtsu Nutraceuticals Research Institute, Otsuka Pharmaceutical Co., Ltd., Shiga, Japan.
Tomohiro KawaharaOtsu Nutraceuticals Research Institute, Otsuka Pharmaceutical Co., Ltd., Shiga, Japan.
Yodai KobayashiOtsu Nutraceuticals Research Institute, Otsuka Pharmaceutical Co., Ltd., Shiga, Japan.
Noriyuki KohdaOtsu Nutraceuticals Research Institute, Otsuka Pharmaceutical Co., Ltd., Shiga, Japan.
Kazunari UshidaCollege of Bioscience and Biotechnology, Chubu University, Aichi, Japan.
Akihiko KitamuraResearch Team for Social Participation and Community Health, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Takuji YamadaSchool of Life Science and Technology, Tokyo Institute of Technology, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence linking the gut-brain axis to Alzheimer's disease (AD) is accumulating, but the characteristics of causally important microbes are poorly understood. We perform a fecal microbiome analysis in healthy subjects and those with mild cognitive impairment (MCI) and AD. We find that

Indexed as

Gastrointestinal MicrobiomeAgedAlzheimer DiseaseAmyloid beta-PeptidesBrainCognitionCognitive DysfunctionDementiaFaecalibacterium prausnitziiFemaleGenome, BacterialHumansMaleMetabolomeMetagenomePasteurizationAmyloid beta-PeptidesAlzheimer’s diseaseapplied microbiologycomparative genomicsFaecalibacterium prausnitziigut microbiomegut microbiome-based interventionMCImetagenomemicrobiota-gut-brain axismild cognitive impairment

Identifiers

PMID34622235
PMCPMC8484692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.