Evidence map›Paper›PMID 34622224›Full record

ArticleJAAD international2021

Determination of serum 25-hydroxyvitamin D levels in patients with alopecia areata and their comparison with levels in healthy controls: A cross-sectional study.

Felix Paolo J Lizarondo, Mia Katrina R Gervasio, Charmaine Vanessa S Chamberlin, Charissa Mia S Gnilo, Claudine Y Silva

Open access · goldAbstract read
In one paragraph

Article in JAAD international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Felix Paolo J LizarondoDepartment of Dermatology, Philippine General Hospital, University of the Philippines, Manila, Philippines.
Mia Katrina R GervasioDepartment of Dermatology, Philippine General Hospital, University of the Philippines, Manila, Philippines.
Charmaine Vanessa S ChamberlinDepartment of Dermatology, Philippine General Hospital, University of the Philippines, Manila, Philippines.
Charissa Mia S GniloDepartment of Dermatology, Philippine General Hospital, University of the Philippines, Manila, Philippines.
Claudine Y SilvaDepartment of Dermatology, Philippine General Hospital, University of the Philippines, Manila, Philippines.
University of the Philippines Manila · PHPhilippine General Hospital · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlopecia areata (AA) has been postulated to be an autoimmune disease affecting the hair follicles. Because vitamin D receptors are present in the immune system and hair follicles, vitamin D has been hypothesized to affect the disease.

objectiveThe aim of this study was to determine serum 25-hydroxyvitamin D levels and the percentage of vitamin D deficiency in AA patients and compare them with those in healthy controls in a Philippine tertiary hospital.

methodsThis cross-sectional study included 29 AA patients and 29 healthy controls. The serum 25-hydroxyvitamin D levels were determined using the chemiluminescent immunoassay method.

resultsThere was no significant difference in the mean vitamin D levels between AA patients (24.41 ± 6.87 ng/mL) and healthy controls (24.68 ± 6.68 ng/mL) ( LIMITATIONS: This study involved a limited number of patients in an urbanized area in the Philippines, and majority of the AA cases seen had mild AA.

conclusionThe trend toward the increased percentage of vitamin D-deficient individuals among AA patients seen in this study may provide insight into the association of vitamin D with AA.

Indexed as

AA, alopecia areataalopecia areatacross-sectionalPhilippinesSALT, severity of alopecia toolserum 25-hydroxyvitamin Dvitamin Dvitamin D deficiencyvitamin D levels

Identifiers

PMID34622224
PMCPMC8484040
OpenAlexW3200581454

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.