ArticleBrain communications2021
A category-selective semantic memory deficit for animate objects in semantic variant primary progressive aphasia.
Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Role of the Speech-Language Therapist/Pathologist in Primary Progressive Aphasia.Neurology. Clinical practice · 2023Article
- Transcranial Direct Current Stimulation Effects on the Neural Substrate of Conceptual Representations.Brain sciences · 2023Article
- Temporopolar regions of the human brain.Brain : a journal of neurology · 2023Article
- Action goals and the praxis network: an fMRI study.Brain structure & function · 2022Article
- Case Report: Semantic Variant of Primary Progressive Aphasia Associated With Anti-Glial Fibrillary Acid Protein Autoantibodies.Frontiers in immunology · 2021Article
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11 authors at 1 institution in 1 country.
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Abstract
Data are mixed on whether patients with semantic variant primary progressive aphasia exhibit a category-selective semantic deficit for animate objects. Moreover, there is little consensus regarding the neural substrates of this category-selective semantic deficit, though prior literature has suggested that the perirhinal cortex and the lateral posterior fusiform gyrus may support semantic memory functions important for processing animate objects. In this study, we investigated whether patients with semantic variant primary progressive aphasia exhibited a category-selective semantic deficit for animate objects in a word-picture matching task, controlling for psycholinguistic features of the stimuli, including frequency, familiarity, typicality and age of acquisition. We investigated the neural bases of this category selectivity by examining its relationship with cortical atrophy in two primary regions of interest: bilateral perirhinal cortex and lateral posterior fusiform gyri. We analysed data from 20 patients with semantic variant primary progressive aphasia (mean age = 64 years, S.D. = 6.94). For each participant, we calculated an animacy index score to denote the magnitude of the category-selective semantic deficit for animate objects. Multivariate regression analysis revealed a main effect of animacy (
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