Evidence map›Paper›PMID 34622149›Full record

ArticleiScience2021

Evaluating methods and protocols of ferritin-based magnetogenetics.

Miriam Hernández-Morales, Victor Han, Richard H Kramer, Chunlei Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Genetics-Based Targeting Strategies for Precise Neuromodulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  3. Article
  4. Electrophysiological Mechanisms and Validation of Ferritin-Based Magnetogenetics for Remote Control of Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  5. Review
  6. Article
  7. Magnetogenetic cell activation using endogenous ferritin.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Miriam Hernández-MoralesDepartment of Electrical Engineering and Computer Sciences, University of California, 505 Cory Hall MC# 1770, Berkeley, CA 94720, USA.
Victor HanDepartment of Electrical Engineering and Computer Sciences, University of California, 505 Cory Hall MC# 1770, Berkeley, CA 94720, USA.
Richard H KramerDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
Chunlei LiuDepartment of Electrical Engineering and Computer Sciences, University of California, 505 Cory Hall MC# 1770, Berkeley, CA 94720, USA.
University of California, Berkeley · US

Funding

Interrogating Biophysical Mechanisms of Magnetogenetic Cell Stimulation at Radio FrequenciesR01NS110554 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI LIU, CHUNLEI · 2019 to 2023
$2.5M
NINDS NIH HHS R01 NS110554
6 · The paper itself

Abstract

FeRIC (Ferritin iron Redistribution to Ion Channels) is a magnetogenetic technique that uses radiofrequency (RF) alternating magnetic fields to activate the transient receptor potential channels, TRPV1 and TRPV4, coupled to cellular ferritins. In cells expressing ferritin-tagged TRPV, RF stimulation increases the cytosolic Ca

Indexed as

BioelectromagneticsBiology experimental methodsGenetics

Identifiers

PMID34622149
PMCPMC8479696
OpenAlexW3198309076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.