Evidence map›Paper›PMID 34622148›Full record

ArticleiScience2021

Ezh2 harnesses the intranuclear actin cytoskeleton to remodel chromatin in differentiating Th cells.

Moran Titelbaum, Boris Brant, Daniel Baumel, Alina Burstein-Willensky, Shira Perez, Yiftah Barsheshet, Orly Avni

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Recent advances in nuclear actin research.Nucleus (Austin, Tex.) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Analysis of Polycomb Epigenetic Marks in HeLa Spheroids.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Moran TitelbaumAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Boris BrantAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Daniel BaumelAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Alina Burstein-WillenskyAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Shira PerezAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Yiftah BarsheshetAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Orly AvniAzrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Bar-Ilan University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following their first interaction with the antigen, quiescent naive T-helper (Th; CD4

Indexed as

Biological sciencesCell biologyImmunology

Identifiers

PMID34622148
PMCPMC8479699
OpenAlexW3197270799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.