ArticleJGH open : an open access journal of gastroenterology and hepatology2021
Accurate reflection of hepatic venous pressure gradient by spleen stiffness measurement in patients with low controlled attenuation parameter values.
Article in JGH open : an open access journal of gastroenterology and hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Predictive value of subharmonic-aided pressure estimation for diagnosing clinically significant portal hypertension.Scientific reports · 2025Article
- Use of Noninvasive Tests to Assess Clinically Significant Portal Hypertension and Response to Beta-Blockers.Gastro hep advances · 2025Review
- Diagnostic accuracy of ultrasound-derived fat fraction for the detection and quantification of hepatic steatosis in patients with liver biopsy.Journal of medical ultrasonics (2001) · 2025Article
- Spleen stiffness measurement as a non-invasive assessment in patients with portal hypertension.eGastroenterology · 2024Review
- Lymphatic drainage dysfunction via narrowing of the lumen of cisterna chyli and thoracic duct after luminal dilation.Hepatology international · 2023Article
- Spleen stiffness: a predictive factor of dismal prognosis in liver cirrhosis.Clinical journal of gastroenterology · 2023Review
- Gastroesophageal varices evaluation using spleen-dedicated stiffness measurement by vibration-controlled transient elastography.JGH open : an open access journal of gastroenterology and hepatology · 2022Article
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Authors and funding
9 authors.
Funding
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Abstract
BACKGROUND AND
aimSpleen stiffness measurement (SSM) is useful for assessing portal hypertension. It is unclear whether SSM values are appropriate because vibration-controlled transient elastography (VCTE) does not generate B-mode images. This study aimed to confirm whether the controlled attenuation parameter (CAP) measured in the spleen can predict the accuracy of SSM.
methodsThis retrospective study enrolled 349 patients who underwent SSM using VCTE from January 2012 to December 2020. Consecutive patients were classified into the pilot set (SSM and hepatic venous pressure gradient [HVPG] were measured) and the validation set (SSM was measured without HVPG). In the pilot set, scatter plots with a nonparametric contour line were created. Logistic regression analysis was performed to predict outliers outside the 50% contour line.
resultsThe values of CAP could distinguish the outliers in scatter plots between the HPVG and SSM in both univariate and multivariate analyses (cutoff, 118 dB/m). The correlation of SSM with HVPG (
conclusionFor patients with CAP <118 dB/m, SSM is a feasible predictor of HVPG.
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