Evidence map›Paper›PMID 34621894›Full record

ArticleBioMed research international2021

Xianling Gubao Capsule Prevents Cadmium-Induced Kidney Injury.

Jian Huang, Xiao-Tong Ma, Duo-Duo Xu, Bao-Jin Yao, Da-Qing Zhao, Xiang-Yang Leng, Jia Liu

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Determination of the Combined Effects of Asian Herbal Medicine with Calcium and/or Vitamin D Supplements on Bone Mineral Density in Primary Osteoporosis: A Systematic Review and Meta-Analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Pooled it
  2. Article
  3. Article
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  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jian HuangDepartment of Pharmaceutical Science, Changchun University of Chinese Medicine, Changchun, China.ORCID https://orcid.org/0000-0003-4248-6101
Xiao-Tong MaDepartment of Pharmaceutical Science, Changchun University of Chinese Medicine, Changchun, China.ORCID https://orcid.org/0000-0001-8323-7553
Duo-Duo XuDepartment of Pharmaceutical Science, Changchun University of Chinese Medicine, Changchun, China.ORCID https://orcid.org/0000-0002-5982-8326
Bao-Jin YaoJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China.ORCID https://orcid.org/0000-0002-7542-1585
Da-Qing ZhaoJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin 130117, China.ORCID https://orcid.org/0000-0001-5678-7410
Xiang-Yang LengThe Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin 130117, China.ORCID https://orcid.org/0000-0001-5278-4001
Jia LiuDepartment of Pharmaceutical Science, Changchun University of Chinese Medicine, Changchun, China.ORCID https://orcid.org/0000-0003-1889-6071
Changchun University of Chinese Medicine · CNThe Affiliated Hospital to Changchun University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Xianling Gubao Capsule (XGC), a kind of capsule preparation of Chinese herbal officially approved for sale by the National Medical Products Administration (NMPA), has the effect of tonifying kidney and strengthening bones. Although the impact of XGC in treating bone diseases has been widely studied, the effect of XGC in kidney injury is unknown yet. The kidney injury model is established by intraperitoneal injection with cadmium chloride (CdCl

Indexed as

AnimalsAutophagyBlood Urea NitrogenCadmiumCapsulesCreatinineDrugs, Chinese HerbalFemaleGene Expression RegulationKidneyMiceMice, Inbred C57BLRNA, MessengerCadmiumCapsulesCreatinineDrugs, Chinese HerbalRNA, Messengerxian ling gu bao

Identifiers

PMID34621894
PMCPMC8492235
OpenAlexW3203484337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.