Evidence map›Paper›PMID 34621771›Full record

ArticleFrontiers in nutrition2021

The Effect of Oral Nutritional Formula With Three Different Proteins on Type 2 Diabetes Mellitus

Ye Jia, Yue Leng, Aliannys Lazára Puente Cruz, Chun Ling Bao, Bin Bao, Wenhui Wu, Peipei Wang, Ming Ma

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ye JiaShanghai Ocean University, College of Food Science and Technology, Shanghai, China.
Yue LengShanghai Ocean University, College of Food Science and Technology, Shanghai, China.
Aliannys Lazára Puente CruzGrupo Empresarial de la Industria Alimentaria, Havana, Cuba.
Chun Ling BaoEast Hospital of Shanghai Sixth People's Hospital, Shanghai, China.
Bin BaoShanghai Ocean University, College of Food Science and Technology, Shanghai, China.
Wenhui WuShanghai Ocean University, College of Food Science and Technology, Shanghai, China.
Peipei WangShanghai Ocean University, College of Food Science and Technology, Shanghai, China.
Ming MaShanghai Ocean University, College of Food Science and Technology, Shanghai, China.
Shanghai Ocean University · CNInstituto de Investigaciones Avícolas · CUShanghai Sixth People's Hospital · CNTarim University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral nutritional (ON) products are an effective way to treat patients with type 2 diabetes mellitus (T2DM) whose gastrointestinal functions are normal. The influence of ON formula prepared with three different proteins on T2DM was studied. The hyperglycaemic mouse model using a high-fat diet (HFD) combined with an intraperitoneal injection of streptozotocin (STZ) was used to simulate T2DM. The study was done for 15 weeks using seven groups of mice: control group (CG, normal mice, and normal food), non-treated group (BG, diabetic mice, and normal food), positive control group (PG, diabetic mice, and HFD), soybean protein group (SPG, diabetic mice, and HFD), silkworm pupa protein group (SPPG, diabetic mice, and HFD), whey protein group (LPG, diabetic mice, and HFD), and whey protein combined with silkworm pupa protein group (LCSSPG, diabetic mice, and HFD). The plasma levels of total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were analyzed on weeks 2, 10, 12, 14, and 15. The concentration of total protein (TP) and albumin (ALB) of the plasma was increased in SPG, SPPG, and PG comparing with BG (

Indexed as

oral nutritional formulasilkworm pupa proteinsoybean proteintype 2 diabetes mellituswhey protein

Identifiers

PMID34621771
PMCPMC8490655
OpenAlexW3201241345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.