Evidence map›Paper›PMID 34621727›Full record

ReviewFrontiers in bioengineering and biotechnology2021

Non-Invasive Electrochemical Biosensors for TNF-α Cytokines Detection in Body Fluids.

Yang Lu, Qingqing Zhou, Lin Xu

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Recent Progresses in Electrochemical DNA Biosensors for SARS-CoV-2 Detection.Frontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yang LuDepartment of Cardiovascular, The Second Hospital of Jilin University, Jilin University, Changchun, China.
Qingqing ZhouState Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun, China.
Lin XuState Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The measurement of pro-inflammatory cytokine tumour necrosis factor-alpha (TNF-α), which is an important indicator of the inflammatory process, has received increasing attention recently because it is easy to extract from body fluid and serves as an early sign of a serious systemic inflammatory disease. Developing fast and simple detection methods to quantify the concentration of TNF-α is essential. Saliva, tears, and urine, which can easily be sampled in a non-invasive way, are considered to be important matrices for monitoring and assessing the physiological status of humans; importantly, they also provide an ideal window for monitoring the concentration of TNF-α. As a fast, accurate, inexpensive, portable, and scalable method, electrochemical biosensors are very promising for biomarker detection in matrices obtained in a non-invasive manner. This review summarises and compares the electrochemical biosensors for the detection of TNF-α in a non-invasive manner and highlights recent advances and future prospects in developing high-performance electrochemical platforms for noninvasive measurement of TNF-α.

Indexed as

cardiovascular diseasediease biomarkerelectrochemical biosensornon-invasiveTNF-α cytokines

Identifiers

PMID34621727
PMCPMC8490748

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.