Evidence map›Paper›PMID 34621649›Full record

ArticleImaging science in dentistry2021

Head and neck radiotherapy-induced changes in dentomaxillofacial structures detected on panoramic radiographs: A systematic review.

Luciana Munhoz, Danielle Ayumi Nishimura, Christyan Hiroshi Iida, Plauto Christopher Aranha Watanabe, Emiko Saito Arita

Open access · goldAbstract read
In one paragraph

Article in Imaging science in dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Assessment of the Advancement of Alveolar Bone Loss in Canine Patients Receiving Definitive Radiotherapy for Sinonasal Tumors.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2026
    Article
  2. Radiographic changes on panoramic imaging following intensity-modulated radiation therapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Luciana MunhozDepartment of Stomatology, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-2375-5935
Danielle Ayumi NishimuraDepartment of Stomatology, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-1720-8759
Christyan Hiroshi IidaDepartment of Stomatology, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-3052-2275
Plauto Christopher Aranha WatanabeDepartment of Stomatology, Public Oral Health, and Forensic Dentistry, Ribeirão Preto Dental School, University of São Paulo, Ribeirão Preto, Brazil.ORCID https://orcid.org/0000-0001-5524-1395
Emiko Saito AritaDepartment of Stomatology, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-1831-4844
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to summarize the impact of neck and head radiation treatment on maxillofacial structures detected on panoramic radiographs. MATERIALS AND

methodsIn this systematic review, the authors searched PubMed Central, Embase, Scopus, Cochrane Central Register of Controlled Trials, Web of Science, and Google Scholar for original research studies up to February 2020 that included the following Medical Subject Headings keywords: words related to "radiotherapy" and synonyms combined with keywords related to "panoramic radiography" and "oral diagnosis" and synonyms. Only original studies in English that investigated the maxillofacial effects of radiotherapy via panoramic radiographs were included. The quality of the selected manuscripts was evaluated by assessing the risk of bias using Cochrane's ROBINS-I tool for non-randomized studies.

resultsThirty-three studies were eligible and included in this review. The main objectives pertained to the assessment of the effects of radiation on maxillofacial structures, including bone architecture alterations, periodontal space widening, teeth development abnormalities, osteoradionecrosis, and implant bone loss. The number of participants evaluated ranged from 8 to 176.

conclusionThe interaction between ionizing radiation and maxillofacial structures results in hazard to the tissues involved, particularly the bone tissue, periosteum, connective tissue of the mucosa, and endothelium. Hard tissue changes due to radiation therapy can be detected on panoramic radiographs.

Indexed as

Diagnosis, OralRadiation EffectsRadiograph, PanoramicRadiotherapy

Identifiers

PMID34621649
PMCPMC8479433
OpenAlexW3160621539

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.