Evidence map›Paper›PMID 34621276›Full record

ReviewFrontiers in immunology2021

Granulocytic Myeloid-Derived Suppressor Cells in Cystic Fibrosis.

Samantha L Tucker, Demba Sarr, Balázs Rada

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Research progress on T-cell responses inFrontiers in microbiology · 2026
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Samantha L TuckerDepartment of Infectious Diseases, College of Veterinary Medicine, The University of Georgia, Athens, GA, United States.
Demba SarrDepartment of Infectious Diseases, College of Veterinary Medicine, The University of Georgia, Athens, GA, United States.
Balázs RadaDepartment of Infectious Diseases, College of Veterinary Medicine, The University of Georgia, Athens, GA, United States.
University of Georgia · US

Funding

Neutrophil extracellular traps in cystic fibrosisR01HL136707 · NHLBI · UNIVERSITY OF GEORGIA · PI RADA, BALAZS · 2018 to 2021
$2.6M
NHLBI NIH HHS R01 HL136707
6 · The paper itself

Abstract

Cystic Fibrosis (CF) is a genetic disease that causes chronic and severe lung inflammation and infection associated with high rates of mortality. In CF, disrupted ion exchange in the epithelium results in excessive mucus production and reduced mucociliary clearance, leading to immune system exacerbation and chronic infections with pathogens such as

Indexed as

Immune EvasionArginaseCystic FibrosisCytotoxicity, ImmunologicGranulocytesHumansMyeloid-Derived Suppressor CellsNeutrophilsPersistent InfectionPseudomonas aeruginosaPseudomonas InfectionsTh17 CellsT-Lymphocytes, RegulatoryARG1 protein, humanArginasecystic fibrosisgMDSCimmunosuppressionmyeloid-derived suppressor cellneutrophil

Identifiers

PMID34621276
PMCPMC8490623
OpenAlexW3199460540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.