Evidence map›Paper›PMID 34621244›Full record

ArticleFrontiers in endocrinology2021

Sex Dimorphic Associations of Gestational Diabetes Mellitus With Cord Plasma Fatty Acid Binding Protein 4 and Estradiol.

Xin Liu, Tao Zheng, Ya-Jie Xu, Meng-Nan Yang, Wen-Juan Wang, Rong Huang, Guang-Hui Zhang, Yu-Na Guo, Jun Zhang, Fengxiu Ouyang and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Xin LiuMinistry of Education-Shanghai Key Laboratory of Children's Environmental Health, Early Life Health Institute, Department of Developmental and Behavioral Pediatric & Child Primary Care, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tao ZhengDepartment of Obstetrics and Gynecology, Xinhua Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Ya-Jie XuMinistry of Education-Shanghai Key Laboratory of Children's Environmental Health, Early Life Health Institute, Department of Developmental and Behavioral Pediatric & Child Primary Care, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Meng-Nan YangMinistry of Education-Shanghai Key Laboratory of Children's Environmental Health, Early Life Health Institute, Department of Developmental and Behavioral Pediatric & Child Primary Care, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wen-Juan WangMinistry of Education-Shanghai Key Laboratory of Children's Environmental Health, Early Life Health Institute, Department of Developmental and Behavioral Pediatric & Child Primary Care, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Rong HuangLunenfeld-Tanenbaum Research Institute, Prosserman Centre for Population Health Research, Department of Obstetrics and Gynecology, Mount Sinai Hospital, Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Guang-Hui ZhangDepartment of Clinical Assay Laboratory, Xinhua Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Yu-Na GuoDepartment of Obstetrics and Gynecology, International Peace Maternity and Child Health Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
Jun ZhangMinistry of Education-Shanghai Key Laboratory of Children's Environmental Health, Early Life Health Institute, Department of Developmental and Behavioral Pediatric & Child Primary Care, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Fengxiu OuyangMinistry of Education-Shanghai Key Laboratory of Children's Environmental Health, Early Life Health Institute, Department of Developmental and Behavioral Pediatric & Child Primary Care, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Fei LiMinistry of Education-Shanghai Key Laboratory of Children's Environmental Health, Early Life Health Institute, Department of Developmental and Behavioral Pediatric & Child Primary Care, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhong-Cheng LuoMinistry of Education-Shanghai Key Laboratory of Children's Environmental Health, Early Life Health Institute, Department of Developmental and Behavioral Pediatric & Child Primary Care, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Jiao Tong University · CNXinHua Hospital · CNLunenfeld-Tanenbaum Research Institute · CAUniversity of Toronto · CA

Funding

CIHR 158616
6 · The paper itself

Abstract

Fatty acid binding protein 4 (FABP4) has been associated with insulin resistance. Gestational diabetes mellitus (GDM) impairs fetal insulin sensitivity. Female newborns are more insulin resistant than male newborns. We sought to evaluate the association between GDM and cord blood FABP4, and explore potential sex dimorphic associations and the roles of sex hormones. This was a nested case-control study in the Shanghai Birth Cohort, including 153 pairs of newborns in GDM

Indexed as

AdiponectinCase-Control StudiesCohort StudiesDiabetes, GestationalEstradiolFatty Acid-Binding ProteinsFemaleHumansInfant, NewbornLeptinMalePregnancySex CharacteristicsSpinal CordTestosteroneAdiponectinEstradiolFABP4 protein, humanFatty Acid-Binding ProteinsLeptinTestosteroneadiponectinestradiol (E2)fatty acid binding protein 4 (FABP4)gestational diabetes mellitus (GDM)sex dimorphismtestosterone

Identifiers

PMID34621244
PMCPMC8490798
OpenAlexW3199143976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.