ArticleFrontiers in physiology2021
Spleen Contraction During Sudden Eupneic Hypoxia Elevates Hemoglobin Concentration.
Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Physiology of nitrogen: A life or death matter.Experimental physiology · 2026Review
- Effects of Apnoea versus Normal Breathing on Physiological Responses during High-Intensity Interval Training in Swimming.Journal of human kinetics · 2025Article
- The application of breath-holding in sports: physiological effects, challenges, and future directions.European journal of applied physiology · 2025Review
- Differential expression of HIF-1α and its hypoxia-related inducers in the spleens of plateau yaks and plain yellow cattle.Histology and histopathology · 2025Article
- Physiologic response to distance diving in healthy children and young adults.Frontiers in sports and active living · 2025Article
- On the mechanisms of stress-induced human spleen contraction: training for a higher blood oxygen-carrying capacity.European journal of applied physiology · 2024Review
- Effect of exercise intensity and apnea on splenic contraction and hemoglobin increase in well-trained cross-country skiers.European journal of applied physiology · 2024Article
- Article
- Relationship between muscle sympathetic nerve activity and rapid increases in circulating leukocytes during experimental muscle pain.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024Article
- Sex-based variations in breath-holding: oxygen storage and diving response among non-divers.Frontiers in physiology · 2024Article
- Splenic contraction and cardiovascular responses are augmented during apnea compared to rebreathing in humans.Frontiers in physiology · 2023Article
- Test-retest reliability of splenic volume assessment by ultrasonography.Scientific reports · 2022Article
- Increased spleen volume provoked by temperate head-out-of-water immersion.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Article
- Relationship between spleen size and exercise tolerance in advanced heart failure patients with a left ventricular assist device.BMC research notes · 2022Article
- Eight weeks of dry dynamic breath-hold training results in larger spleen volume but does not increase haemoglobin concentration.Frontiers in physiology · 2022Article
- Chemoreflex Control as the Cornerstone in Immersion Water Sports: Possible Role on Breath-Hold.Frontiers in physiology · 2022Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The spleen contracts progressively during moderate normobaric hypoxia exposure of 20 min, which elevates hemoglobin concentration (Hb). However, acute hypoxia exposure could be shorter and more severe when oxygen systems fail during, e.g., high-altitude sky diving, aircraft cabin pressure drop, balloon flights, extreme altitude climbing, and in some maladies. We aimed to evaluate the speed and magnitude of spleen contraction during short exposure to extreme eupneic hypoxia and its subsequent recovery on oxygen. Eight female and seven male volunteers were exposed to normobaric hypoxia (10% oxygen) for 10 min during sitting rest, followed by 10 min on 100% oxygen. Heart rate (HR), arterial oxygen saturation (SpO
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Registered trials
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