Evidence map›Paper›PMID 34621180›Full record

ArticleFrontiers in physiology2021

VE-Cadherin and Vesicles Differentially Regulate Lymphatic Vascular Permeability to Solutes of Various Sizes.

Melanie Jannaway, Joshua P Scallan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. A Hierarchical Mechanotransduction System: From Macro to Micro.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Lymphatic Vascular Permeability.Cold Spring Harbor perspectives in medicine · 2022
    Review
  15. Lymphangiogenesis and Lymphatic Barrier Dysfunction in Renal Fibrosis.International journal of molecular sciences · 2022
    Review
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Melanie JannawayMolecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Joshua P ScallanMolecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
University of South Florida · US

Funding

Pathways Regulating Lymphatic Vessel Permeability and Valve FormationR01HL142905 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI SCALLAN, JOSHUA PAUL · 2019 to 2023
$2.2M
NHLBI NIH HHS R01 HL142905
6 · The paper itself

Abstract

Lymphatic vascular permeability prevents lymph leakage that is associated with lymphedema, lymphatic malformations, obesity, and inflammation. However, the molecular control of lymphatic permeability remains poorly understood. Recent studies have suggested that adherens junctions and vesicle transport may be involved in regulating lymphatic vessel permeability. To determine the contribution of each transport pathway, we utilized an

Indexed as

barrier functionendotheliumlymphatic vasculaturemolecular weightsolute flux

Identifiers

PMID34621180
PMCPMC8491776
OpenAlexW3200245509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.