Evidence map›Paper›PMID 34621121›Full record

ArticleClinical interventions in aging2021

Intraoperative Hypotension and Related Risk Factors for Postoperative Mortality After Noncardiac Surgery in Elderly Patients: A Retrospective Analysis Report.

Benhui Zhao, Xingtong Chen, Qian Chen, Gaoming Li, Zhe Chen, Ziheng Yang, Li Gu, Xudong Xiao, Zhen Wang, Jiaolin Ning and 4 more

Open access · goldAbstract read
In one paragraph

Article in Clinical interventions in aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Risk factors for intraoperative hypotension during cardiac surgery.Indian journal of thoracic and cardiovascular surgery · 2025
    Article
  9. Article
  10. Observational
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 2 countries.

Benhui Zhao *Department of Anesthesiology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.
Xingtong Chen *Department of Anesthesiology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.ORCID 0000-0003-0581-6087
Qian ChenDepartment of Anesthesiology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.
Gaoming LiDepartment of Health Statistics, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.
Zhe ChenQuality Management and Control Department, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.
Ziheng YangDepartment of Anesthesiology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.
Li GuDepartment of Anesthesiology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.
Xudong XiaoDepartment of Anesthesiology, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.
Zhen WangDepartment of Anesthesiology.
Jiaolin NingDepartment of Anesthesiology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.
Bin YiDepartment of Anesthesiology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.
Kaizhi LuDepartment of Anesthesiology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.
Hongyan ZhangHospital Office, Daping Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.
Jianteng GuDepartment of Anesthesiology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.ORCID 0000-0002-5339-9030
Army Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlood pressure fluctuation is very common during non-cardiac surgery in elderly. This retrospective study was to analyse whether intraoperative hypotension in elderly and other risk factors relate to the postoperative mortality.

methodsA total of 118 cases (Observational group), who underwent noncardiac surgery in three medical centers between September 2014 and March 2017, and died in the hospital after the noncardiac surgery. With 1:2 ratio of propensity matching, 236 survival cases (Control group) were selected for comparison analyses with the death cases. Intraoperative blood pressure and perioperative parameters from both groups were collected from electronic anaesthesia charts. Data were analysed with univariate logistic regression analysis where variables with

resultsThere are five risk factors related to postoperative death in elderly patients: ASA grade, COPD, emergency surgery, general anesthesia, 60 < MAP ≤ 65mmHg (OR > 1), and one factor may reduce the risk of postoperative mortality, which is PACU therapy (OR < 1). Compared with the Control group, the Observational group had a higher proportion of cerebral hernia, kidney injury and trauma (

conclusionThe intraoperative MAP of geriatric patients lower than 65mmHg is highly related to the postoperative mortality. Elderly patients with emergency surgery, high ASA grade and a history of COPD have an increased risk of postoperative mortality. General anesthesia is a risk factor for postoperative death in elderly patients, and the PACU therapy is a protective factor to avoid postoperative death.

trial registrationThis study has been retrospectively registered in the Chinese Clinical Trials Registry (ChiCTR2000038912, 10/10/2020).

Indexed as

HypotensionPostoperative ComplicationsAgedAnesthesia, GeneralHumansRetrospective StudiesRisk FactorsCOPDgeriatric patientsintraoperative hypotensionnon-cardiac surgerypostoperative mortality

Identifiers

PMID34621121
PMCPMC8491785
OpenAlexW3204217324

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.