Evidence map›Paper›PMID 34621080›Full record

ArticleBiometrika2020

Sparse semiparametric canonical correlation analysis for data of mixed types.

Grace Yoon, Raymond J Carroll, Irina Gaynanova

Abstract read
In one paragraph

Article in Biometrika, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Artificial intelligence to investigate metabolomics data for precision medicine.Metabolomics : Official journal of the Metabolomic Society · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Canonical correlation analysis for elliptical copulas.Journal of multivariate analysis · 2021
    Article
  15. Fast computation of latent correlations.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2021
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Grace YoonDepartment of Statistics, Texas A&M University, College Station, Texas 77843, U.S.A.
Raymond J CarrollDepartment of Statistics, Texas A&M University, College Station, Texas 77843, U.S.A.
Irina GaynanovaDepartment of Statistics, Texas A&M University, College Station, Texas 77843, U.S.A.

Funding

Measurement Error, Nutrition, Physical Activity and CancerU01CA057030 · NCI · TEXAS A&M UNIVERSITY · PI CARROLL, RAYMOND J. · 2015 to 2019
$2.8M
Nutrition, Biostatistics & Bioinformatics Training GrantT32CA090301 · NCI · TEXAS A&M UNIVERSITY · PI CARROLL, RAYMOND J. · 2016 to 2020
$712k
NCI NIH HHS T32 CA090301NCI NIH HHS U01 CA057030
6 · The paper itself

Abstract

Canonical correlation analysis investigates linear relationships between two sets of variables, but often works poorly on modern datasets due to high-dimensionality and mixed data types (continuous/binary/zero-inflated). We propose a new approach for sparse canonical correlation analysis of mixed data types that does not require explicit parametric assumptions. Our main contribution is the use of truncated latent Gaussian copula to model the data with excess zeroes, which allows us to derive a rank-based estimator of latent correlation matrix without the estimation of marginal transformation functions. The resulting semiparametric sparse canonical correlation analysis method works well in high-dimensional settings as demonstrated via numerical studies, and application to the analysis of association between gene expression and micro RNA data of breast cancer patients.

Indexed as

BICGaussian copula modelKendall’s τLatent correlation matrixTruncated continuous variableZero-inflated data

Identifiers

PMID34621080
PMCPMC8494134

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.