Evidence map›Paper›PMID 34620945›Full record

ArticleScientific reports2021

lncRNA-disease association prediction based on latent factor model and projection.

Bo Wang, Chao Zhang, Xiao-Xin Du, Jian-Fei Zhang

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bo WangCollege of Computer and Control Engineering, Qiqihar University, Qiqihar, 161006, People's Republic of China. drbowang@163.com.
Chao ZhangCollege of Computer and Control Engineering, Qiqihar University, Qiqihar, 161006, People's Republic of China.
Xiao-Xin DuCollege of Computer and Control Engineering, Qiqihar University, Qiqihar, 161006, People's Republic of China.
Jian-Fei ZhangCollege of Computer and Control Engineering, Qiqihar University, Qiqihar, 161006, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Computer aided research of lncRNA-disease association is an important way to study the development of lncRNA-disease. The correlation analysis of existing data, the establishment of prediction model, prediction of unknown lncRNA-disease association, can make the biological experiment targeted, improve the accuracy of biological experiment. In this paper, a lncRNA-disease association prediction model based on latent factor model and projection is proposed (LFMP). This method uses lncRNA-miRNA association data and miRNA-disease association data to predict the unknown lncRNA-disease association, so this method does not need lncRNA-disease association data. The simulation results show that under the LOOCV framework, the AUC of LFMP can reach 0.8964. Better than the latest results. Through the case study of lung and colorectal tumors, LFMP can effectively infer the undetected lncRNA-disease association.

Indexed as

Colorectal NeoplasmsComputational BiologyComputer SimulationFemaleGenetic Predisposition to DiseaseHumansLung NeoplasmsMaleRNA, Long NoncodingRNA, Long Noncoding

Identifiers

PMID34620945
PMCPMC8497550

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.