ArticleNPJ Parkinson's disease2021
Decreased frontotemporal connectivity in patients with parkinson's disease experiencing face pareidolia.
Article in NPJ Parkinson's disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Enhanced visual illusions in Parkinson's disease with cardiovascular autonomic failure.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025Article
- Pareidolia and Constipation in De Novo Parkinson's Disease: Symptomatic Markers of a Shared Clinical Pattern.Cureus · 2025Article
- Sentence comprehension in Lewy body diseases: a functional magnetic resonance imaging study.Brain communications · 2025Article
- Predicting Onset of Visual Hallucinations Using Pareidolias: A Qualitative Exploration of the Ethics of a Digital App to Detect a Possible Biomarker.Journal of technology in behavioral science · 2024Article
- Article
- Noise Pareidolia Test in Parkinson's Disease and Atypical Parkinsonian Syndromes: A Retrospective Study.Cureus · 2024Article
- Clinical correlates of pareidolias and color discrimination deficits in idiopathic REM sleep behavior disorder and Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2024Article
- No common factor for illusory percepts, but a link between pareidolia and delusion tendency: A test of predictive coding theory.Frontiers in psychology · 2022Article
- Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The precise neural underpinnings of face pareidolia in patients with Parkinson's disease (PD) remain unclear. We aimed to clarify face recognition network abnormalities associated with face pareidolia in such patients. Eighty-three patients with PD and 40 healthy controls were recruited in this study. Patients with PD were classified into pareidolia and nonpareidolia groups. Volumetric analyses revealed no significant differences between the pareidolia (n = 39) and nonpareidolia (n = 44) patient groups. We further observed decreased functional connectivity among regions of interest in the bilateral frontotemporal lobes in patients with pareidolia. Seed-based analysis using bilateral temporal fusiform cortices as seeds revealed significantly decreased connectivity with the bilateral inferior medial prefrontal cortices in the pareidolia group. Post hoc regression analysis further demonstrated that the severity of face pareidolia was negatively correlated with functional connectivity between the bilateral temporal fusiform and medial prefrontal cortices. Our findings suggest that top-down modulation of the face recognition network is impaired in patients with PD experiencing face pareidolia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.