Evidence map›Paper›PMID 34620627›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2021

Neighborhood Socioeconomic Deprivation and Mortality in Children with Central Nervous System Tumors.

Maral Adel Fahmideh, Jeremy M Schraw, Murali Chintagumpala, Philip J Lupo, Abiodun Olufemi Oluyomi, Michael E Scheurer

Open access · bronzeAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Observational
  2. Article
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  4. Area Deprivation and Pediatric Cancer Mortality: An Analysis of 2000 to 2020 State Cancer Registry Data.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  5. Area-Level Socioeconomic Disadvantage and Post-PICU Outcomes in Children With an Acquired Brain Injury: Single-Center Retrospective Cohort, 2016-2023.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025
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  10. Population-Based Impact of Rurality and Neighborhood-Level Socioeconomic Disadvantage on Pediatric Cancer Mortality in Washington State.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maral Adel FahmidehDepartment of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, Texas. Maral.Adel@bcm.edu.ORCID 0000-0002-9930-8288
Jeremy M SchrawDan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas.
Murali ChintagumpalaDan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas.
Philip J LupoDepartment of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, Texas.ORCID 0000-0003-0978-5863
Abiodun Olufemi Oluyomi *Department of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, Texas.
Michael E Scheurer *Department of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, Texas.ORCID 0000-0002-8379-6088
Baylor College of Medicine · US

Funding

Translational Research Support CoreP30ES030285 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Cheryl L. Walker · 2019 to 2026
$14.7M
NIEHS NIH HHS P30 ES030285
6 · The paper itself

Abstract

backgroundAlthough there is evidence of socioeconomic disparities in survival of children diagnosed with central nervous system (CNS) tumors, the impact of neighborhood socioeconomic deprivation on the survival of these malignancies has not been adequately studied. We investigated the association between area deprivation index (ADI), a measure of neighborhood socioeconomic disadvantage, and pediatric CNS tumor survival.

methodsDemographic and clinical characteristics, geocoded addresses at diagnosis, and vital status of pediatric CNS tumor cases (

resultsThe results showed a significantly increased HR for death among children in the most (HR, 1.29; 95% CI, 1.09-1.51), second-most (HR, 1.18; 95% CI, 1.01-1.38), and third-most disadvantaged census tracts (HR, 1.18; 95% CI, 1.02-1.37) compared with children in the least disadvantaged tracts.

conclusionsChildren living in the most disadvantaged neighborhoods experienced a significantly higher risk of mortality, indicating the important role of socioeconomic disparities in the survival of pediatric CNS tumors. IMPACT: The demographic and socioeconomic disparities identified by this study should be considered when planning treatment strategies for these susceptible groups and thus, lead to a better outcome in socioeconomically disadvantaged children diagnosed with CNS tumors.

Indexed as

Central Nervous System NeoplasmsChildFemaleHealth Status DisparitiesHumansMaleNeighborhood CharacteristicsPoverty AreasRegistriesRetrospective StudiesTexas

Identifiers

PMID34620627
PMCPMC9058976
OpenAlexW3204221153

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.