Evidence map›Paper›PMID 34620590›Full record

ArticleAJNR. American journal of neuroradiology2021

Filtered Diffusion-Weighted MRI of the Human Cervical Spinal Cord: Feasibility and Application to Traumatic Spinal Cord Injury.

S A Murphy, R Furger, S N Kurpad, V E Arpinar, A Nencka, K Koch, M D Budde

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

S A MurphyFrom the Department of Neurosurgery (S.A.M., R.F., S.N.K., M.D.B.) spamurphy@mcw.edu.ORCID 0000-0002-0397-1502
R FurgerFrom the Department of Neurosurgery (S.A.M., R.F., S.N.K., M.D.B.).ORCID 0000-0001-8829-5832
S N KurpadFrom the Department of Neurosurgery (S.A.M., R.F., S.N.K., M.D.B.).ORCID 0000-0003-1548-5453
V E ArpinarCenter for Imaging Research (V.E.A., A.N., K.K.), Medical College of Wisconsin, Milwaukee, Wisconsin.ORCID 0000-0002-3238-4569
A NenckaCenter for Imaging Research (V.E.A., A.N., K.K.), Medical College of Wisconsin, Milwaukee, Wisconsin.ORCID 0000-0001-5268-2718
K KochCenter for Imaging Research (V.E.A., A.N., K.K.), Medical College of Wisconsin, Milwaukee, Wisconsin.ORCID 0000-0003-4490-9761
M D BuddeFrom the Department of Neurosurgery (S.A.M., R.F., S.N.K., M.D.B.).ORCID 0000-0003-4769-5797
Medical College of Wisconsin · USOntario Neurotrauma Foundation · CANorwegian Womens Public Health Association · NO

Funding

Advanced MRI of Spinal Cord InjuryI01RX002751 · VA · CLEMENT J. ZABLOCKI VA MEDICAL CENTER · PI KURPAD, SHEKAR N. · 2019 to 2023
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RRD VA I01 RX002751
6 · The paper itself

Abstract

background and purposeIn traumatic spinal cord injury, DTI is sensitive to injury but is unable to differentiate multiple pathologies. Axonal damage is a central feature of the underlying cord injury, but prominent edema confounds its detection. The purpose of this study was to examine a filtered DWI technique in patients with acute spinal cord injury. MATERIALS AND

methodsThe MR imaging protocol was first evaluated in a cohort of healthy subjects at 3T (

resultsThe high-strength diffusion-weighting perpendicular to the cord suppressed signals from tissues outside of the spinal cord, including muscle and CSF. The parallel ADC acquired from filtered DWI at the level of injury relative to the most cranial region showed a greater decrease (38.71%) compared with the decrease in axial diffusivity acquired by DTI (17.68%).

conclusionsThe results demonstrated that filtered DWI is feasible in the acute setting of spinal cord injury and reveals spinal cord diffusion characteristics not evident with conventional DTI.

Indexed as

Cervical CordSpinal Cord InjuriesFeasibility StudiesHumansMagnetic Resonance ImagingSpinal Cord

Identifiers

PMID34620590
PMCPMC8583257
OpenAlexW3202656322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.