ReviewSeminars in pediatric neurology2021
Localizing the Epileptogenic Zone with Novel Biomarkers.
Review in Seminars in pediatric neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Predicting surgical outcome in drug-resistant epilepsy by combining interictal biomarkers within a machine learning framework.Scientific reports · 2026Article
- Predicting Surgical Outcome in Drug-Resistant Epilepsy by Combining Interictal Biomarkers within a Machine Learning Framework.Research square · 2026Article
- 3D printed pediatric head phantom for assessing deep epileptic sources localization.Computers in biology and medicine · 2026Article
- Brain Volume Correlations and Machine Learning Classification in Epilepsy Diagnosis.Advances in experimental medicine and biology · 2026Article
- Stability Analysis of Linear Time Varying Models Constructed from Intracranial EEG Recordings for Modeling Epileptogenic NetworksAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025Article
- Machine learning on interictal intracranial EEG predicts surgical outcome in drug resistant epilepsy.NPJ digital medicine · 2025Article
- Precision medicine for epilepsy: challenges and perspectives for an optimized clinical care pathway.Frontiers in neurology · 2025Review
- Spatio-temporal independent component classification for localization of seizure onset zone.Frontiers in neurology · 2025Article
- Overlap of spike and ripple propagation onset predicts surgical outcome in epilepsy.Annals of clinical and translational neurology · 2024Article
- Gamma amplitude-envelope correlations are strongly elevated within hyperexcitable networks in focal epilepsy.Scientific reports · 2024Article
- Identifying epileptogenic abnormalities through spatial clustering of MEG interictal band power.Epilepsia open · 2023Article
- Spike propagation mapping reveals effective connectivity and predicts surgical outcome in epilepsy.Brain : a journal of neurology · 2023Article
- The role of superficial and deep layers in the generation of high frequency oscillations and interictal epileptiform discharges in the human cortex.Scientific reports · 2023Article
- Implementation of a Morphological Filter for Removing Spikes from the Epileptic Brain Signals to Improve Identification Ripples.Sensors (Basel, Switzerland) · 2022Article
- Case Report: Laser Ablation Guided by State of the Art Source Imaging Ends an Adolescent's 16-Year Quest for Seizure Freedom.Frontiers in human neuroscience · 2022Article
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Authors and funding
2 authors.
Funding
Abstract
Several noninvasive methods, such as high-density EEG or magnetoencephalography, are currently used to delineate the epileptogenic zone (EZ) during the presurgical evaluation of patients with drug resistant epilepsy (DRE). Yet, none of these methods can reliably identify the EZ by their own. In most cases a multimodal approach is needed. Challenging cases often require the implantation of intracranial electrodes, either through stereo-taxic EEG or electro-corticography. Recently, a growing body of literature introduces novel biomarkers of epilepsy that can be used for analyzing both invasive as well as noninvasive electrophysiological data. Some of these biomarkers are able to delineate the EZ with high precision, augment the presurgical evaluation, and predict the surgical outcome of patients with DRE undergoing surgery. However, the use of these epilepsy biomarkers in clinical practice is limited. Here, we summarize and discuss the latest technological advances in the presurgical neurophysiological evaluation of children with DRE with emphasis on electric and magnetic source imaging, high frequency oscillations, and functional connectivity.
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