Evidence map›Paper›PMID 34620342›Full record

ArticleClinical nutrition ESPEN2021

Malnutrition risk as a negative prognostic factor in COVID-19 patients.

Stefano Mancin, Andrea Bertone, Daniela Cattani, Emanuela Morenghi, Lorena Passadori, Daniela Donizzetti, Fanny Sökeland, Elena Azzolini, Beatrice Mazzoleni

Open access · bronzeAbstract read
In one paragraph

Article in Clinical nutrition ESPEN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  4. Article
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  6. Observational
  7. Long COVID: Is there a kidney link?Frontiers in medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Stefano MancinIRCCS Humanitas Research Hospital Rozzano, Milan, Italy. Electronic address: stefano.mancin@humanitas.it.
Andrea BertoneIRCCS Humanitas Research Hospital Rozzano, Milan, Italy.
Daniela CattaniHumanitas University Pieve Emanuele, Milan, Italy.
Emanuela MorenghiIRCCS Humanitas Research Hospital Rozzano, Milan, Italy; Humanitas University Pieve Emanuele, Milan, Italy.
Lorena PassadoriIRCCS Humanitas Research Hospital Rozzano, Milan, Italy.
Daniela DonizzettiIRCCS Humanitas Research Hospital Rozzano, Milan, Italy.
Fanny SökelandHumanitas University Pieve Emanuele, Milan, Italy.
Elena AzzoliniIRCCS Humanitas Research Hospital Rozzano, Milan, Italy.
Beatrice MazzoleniHumanitas University Pieve Emanuele, Milan, Italy.
IRCCS Humanitas Research Hospital · ITHumanitas University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectiveSARS CoV-2 infection is a disease, whose prevalence has drastically risen in the past year. The aim of this study is to examine a possible association between the risk of malnutrition, clinical outcomes following hospitalisation and morbidity at discharge.

methodsThis study has analysed the medical records of 652 patients hospitalised at Humanitas Research Hospital (Milan, Italy) between 01/03 and 30/04/2020. The risk of malnutrition was identified with the Malnutrition Universal Screening Tool (MUST).

resultsThe cohort was composed of 515 patients. The MUST scale is significantly associated to malnutrition evaluating the morbidity at discharge (discharged 0.27 ± 0.68, discharged with problems 0.40 ± 0.93, deceased 0.64 ± 0.93, p < 0.001), and the clinical outcome following hospitalisation (HR 1.25, 95% CI 1.04-1.51, p = 0.019) is maintained even after correction for age, treated hypertension, admission to an intensive care unit and oxygen therapy). A subgroup analysis addressing patients with a BMI ≥30 shows a significant association between comorbidities such as: arterial hypertension (HR 4.95, 95% CI 1.10-22.22, p = 0.037), diabetes (HR 3.37, 95% CI 1.04-10.89, p = 0.043) and renal failure (HR 3.94, 95% CI 1.36-11.36, p = 0.011).

conclusionsThe results of this study suggest that the risk of malnutrition is a noteworthy indicator that impacts both the clinical outcomes and morbidity at discharge.

Indexed as

COVID-19MalnutritionHospitalizationHumansPrognosisSARS-CoV-2ACE2Immune systemInfectionMalnutritionObesitySARS-CoV-2

Identifiers

PMID34620342
PMCPMC8327593
OpenAlexW3191191465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.