Evidence map›Paper›PMID 34620220›Full record

ArticleJournal of animal science and biotechnology2021

25-hydroxycholecalciferol reverses heat induced alterations in bone quality in finisher broilers associated with effects on intestinal integrity and inflammation.

Huaiyong Zhang, Maryam Majdeddin, Djoere Gaublomme, Bernard Taminiau, Matthieu Boone, Dirk Elewaut, George Daube, Iván Josipovic, Keying Zhang, Joris Michiels

Open access · goldAbstract read
In one paragraph

Article in Journal of animal science and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 43 citations in OpenAlex.

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  19. Germ-Free C57BL/6 Mice Have Increased Bone Mass and Altered Matrix Properties but Not Decreased Bone Fracture Resistance.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Huaiyong Zhang *Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, 9000, Ghent, Belgium.
Maryam Majdeddin *Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, 9000, Ghent, Belgium.
Djoere GaublommeUnit Molecular Immunology and Inflammation, VIB Center for Inflammation Research, Ghent University and Department of Rheumatology, Ghent University Hospital, 9000, Ghent, Belgium.
Bernard TaminiauDepartment of Food Sciences - Microbiology, University of Liège, 4000, Liège, Belgium.
Matthieu BooneGhent University Centre for X-ray Tomography (UGCT), Ghent University, 9000, Ghent, Belgium.
Dirk ElewautUnit Molecular Immunology and Inflammation, VIB Center for Inflammation Research, Ghent University and Department of Rheumatology, Ghent University Hospital, 9000, Ghent, Belgium.
George DaubeDepartment of Food Sciences - Microbiology, University of Liège, 4000, Liège, Belgium.
Iván JosipovicGhent University Centre for X-ray Tomography (UGCT), Ghent University, 9000, Ghent, Belgium.
Keying ZhangKey laboratory of Animal Disease-resistant Nutrition, Ministry of Education, Institute of Animal Nutrition, Sichuan Agricultural University, Ya'an, 611130, Sichuan, China.
Joris MichielsLaboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, 9000, Ghent, Belgium. joris.michiels@ugent.be.ORCID http://orcid.org/0000-0002-9577-0045
Ghent University · BEGhent University Hospital · BEUniversity of Liège · BESichuan Agricultural University · CN

Funding

Bijzonder Onderzoeksfonds BOF.EXP.2017.0007Chinese Government Scholarship [2019]110
6 · The paper itself

Abstract

backgroundAlterations in ambient temperature have been associated with multiple detrimental effects on broilers such as intestinal barrier disruption and dysbiosis resulting in systemic inflammation. Inflammation and 25-hydroxycholecalciferol (25-OH-D

resultsHeat stress (HS) directly induced a decrease in tibia material properties and bone mass, as demonstrated by lower mineral content, and HS caused a notable increase in intestinal permeability. Treatment with dietary 25-OH-D

conclusionsThese data underscore the damage of HS to intestinal integrity and bone health, as well as that dietary 25-OH-D

Indexed as

Bone remodelingHSInflammationIntestinal barrierTibial mass

Identifiers

PMID34620220
PMCPMC8499578
OpenAlexW3203505208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.