Evidence map›Paper›PMID 34620089›Full record

ArticleBMC anesthesiology2021

Efficiency of different flows for apneic oxygenation when using high flow nasal oxygen application - a technical simulation.

W A Wetsch, H Herff, D C Schroeder, D Sander, B W Böttiger, S R Finke

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC anesthesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

W A Wetsch *Department of Anaesthesiology and Critical Care Medicine, University of Cologne, Faculty of Medicine and University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany. wolfgang.wetsch@uk-koeln.de.
H Herff *Department of Anaesthesiology and Critical Care Medicine, University of Cologne, Faculty of Medicine and University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
D C SchroederDepartment of Anaesthesiology and Critical Care Medicine, University of Cologne, Faculty of Medicine and University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
D SanderDepartment of Anaesthesiology and Critical Care Medicine, University of Cologne, Faculty of Medicine and University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
B W BöttigerDepartment of Anaesthesiology and Critical Care Medicine, University of Cologne, Faculty of Medicine and University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
S R FinkeDepartment of Anaesthesiology and Critical Care Medicine, University of Cologne, Faculty of Medicine and University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
University Hospital Cologne · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreoxygenation and application of apneic oxygenation are standard to prevent patients from desaturation e.g. during emergency intubation. The time before desaturation occurs can be prolonged by applying high flow oxygen into the airway. Aim of this study was to scientifically assess the flow that is necessary to avoid nitrogen entering the airway of a manikin model during application of pure oxygen via high flow nasal oxygen.

methodsWe measured oxygen content over a 20-min observation period for each method in a preoxygenated test lung applied to a human manikin, allowing either room air entering the airway in control group, or applying pure oxygen via high flow nasal oxygen at flows of 10, 20, 40, 60 and 80 L/min via nasal cannula in the other groups. Our formal hypothesis was that there would be no difference in oxygen fraction decrease between the groups.

resultsOxygen content in the test lung dropped from 97 ± 1% at baseline in all groups to 43 ± 1% in the control group (p < 0.001 compared to all other groups), to 92 ± 1% in the 10 L/min group, 92 ± 1% in the 20 L/min group, 90 ± 1% in the 40 L/min group, 89 ± 0% in the 60 L/min group and 87 ± 0% in the 80 L/min group. Apart from comparisons 10 l/ min vs. 20 L/min group (p = .715) and 10/L/min vs. 40 L/min group (p = .018), p was < 0.009 for all other comparisons.

conclusionsSimulating apneic oxygenation in a preoxygenated manikin connected to a test lung over 20 min by applying high flow nasal oxygen resulted in the highest oxygen content at a flow of 10 L/min; higher flows resulted in slightly decreased oxygen percentages in the test lung.

Indexed as

Administration, IntranasalApneaManikinsOxygen Inhalation TherapyApneic oxygenationOropharyngeal oxygenation deviceOxygen desaturationSimulation

Identifiers

PMID34620089
PMCPMC8495445
OpenAlexW3204751048

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.