Evidence map›Paper›PMID 34619446›Full record

ArticleThe International journal on drug policy2022

Participants of a mail delivery syringe services program are underserved by other safe sources for sterile injection supplies.

Benjamin T Hayes, Jamie Favaro, Dan Coello, Czarina N Behrends, Andrea Jakubowski, Aaron D Fox

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in The International journal on drug policy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07625917 (Feasibility of Internet-based HIV Prevention Research), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07625917 narecruitingnot on this mapstarted 2025, after this paper: background citation

Feasibility of Internet-based HIV Prevention Research

TypeinterventionalSponsorMontefiore Medical CenterRan2025 to 2028Enrolled500ConditionsHIV Prevention, Injection Drug UseArmsMail delivery of at-home self-administered HIV tests
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Benjamin T HayesDivision of General Internal Medicine, Montefiore Medical Center, Bronx, NY, USA. Electronic address: bhayes@montefiore.org.
Jamie FavaroNEXT Harm Reduction, New York, NY, USA.
Dan CoelloNEXT Harm Reduction, New York, NY, USA.
Czarina N BehrendsPopulation Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Andrea JakubowskiDivision of General Internal Medicine, Montefiore Medical Center, Bronx, NY, USA.
Aaron D FoxDivision of General Internal Medicine, Montefiore Medical Center, Bronx, NY, USA.
Montefiore Medical Center · USHarm Reduction Services · USWeill Cornell Medicine · US

Funding

Patient and Population Health Outcomes Research SWGP30AI124414 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Vinayaka R. Prasad · 2017 to 2026
$28.3M
CTSA Administrative Supplement for Informatics Core: A novel AI/ML system to predict respiratory failure and ARDS in Covid-19 patientsUL1TR002556 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, KIM, MIMI Y · 2018 to 2022
$26.7M
Impact of PTSD and trauma reexposure on buprenorphine maintenance treatment in syringe exchange programsR01DA044878 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI FOX, AARON D · 2017 to 2022
$3.7M
NCATS NIH HHS UL1 TR002556NIAID NIH HHS P30 AI124414NIDA NIH HHS R01 DA044878
6 · The paper itself

Abstract

backgroundIn the United States, accessing sterile injection supplies remains challenging for many people who inject drugs (PWID). Although women are less likely to inject drugs than men, women who do inject are disproportionately affected by IDU-related complications. Needle Exchange Technology (NEXT), the first formal online accessed mail delivery syringe services program (SSP) in the US, may overcome access barriers. We evaluated whether NEXT was reaching women participants and people without access to other safe sources of sterile injection supplies.

methodsThis cross-sectional study examined NEXT participants who enrolled in the mail-delivery SSP from February 2018 through March 2021. All NEXT participants completed an online questionnaire during enrollment, which included sociodemographic and clinical characteristics and injection-related risk factors (including prior sources of sterile injection supplies). Multivariable logistic regression (MVR) was used to examine associations between gender and prior use of safe sources of injection supplies (i.e., SSPs or pharmacies).

results1,032 participants received injection supplies. Median age was 34 and participants were mostly cis-gendered women (55%) and white (93%). 34% reported infection with HCV; women were more likely to report HCV infection than men (38% vs 28%; p < 0.01). 68% of participants acquired injection supplies from less safe sources. Few participants exclusively used safe sources for injection supplies (26%). In adjusted MVR analysis, women participants had significantly lower odds than men of having exclusively used safe sources for injection supplies (adjusted OR 0.71, 95% CI 0.52, 0.98).

conclusionOur findings suggest that NEXT services are utilized by women and people without prior access to sterile injection supplies. Women participants were less likely than men to have exclusively used safe sources for sterile injection supplies. Future research should explore women's preference for mail-delivery over in-person SSPs and determine whether online accessed mail delivery services can reach other underserved populations of PWID.

Indexed as

HIV InfectionsSubstance Abuse, IntravenousAdultCross-Sectional StudiesFemaleHumansMaleNeedle-Exchange ProgramsPostal ServiceSyringesUnited StatesHarm reductionMail deliverySyringe services programWomen

Identifiers

PMID34619446
PMCPMC8755579
OpenAlexW3204001534

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.