The value of open-source clinical science in pandemic response: lessons from ISARIC.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

22 citing papers in PubMed.

1. How to conduct an individual participant data meta-analysis in response to an emerging pathogen: Lessons learned from Zika and COVID-19.Research synthesis methods · 2026
   Review
2. Lightweight transformers for clinical natural language processing.Natural language engineering · 2024
   Article
3. Optimising Clinical Epidemiology in Disease Outbreaks: Analysis of ISARIC-WHO COVID-19 Case Report Form Utilisation.Epidemiologia (Basel, Switzerland) · 2024
   Article
4. Creation of Standardized Common Data Elements for Diagnostic Tests in Infectious Disease Studies: Semantic and Syntactic Mapping.Journal of medical Internet research · 2024
   Article
5. The Ebola Data Platform: A prospective, standardised, clinical dataset collected during the 2013-2016 West African Ebola outbreak.Wellcome open research · 2024
   Article
6. Sex differences in post-acute neurological sequelae of SARS-CoV-2 and symptom resolution in adults after coronavirus disease 2019 hospitalization: an international multi-centre prospective observational study.Brain communications · 2024
   Article
7. Association of cancer and outcomes of patients hospitalized for COVID-19 between 2020 and 2023.F1000Research · 2024
   Article
8. ISO/TS 21564:2019- based Evaluation of a Semantic Map between Variables in the ISARIC Freestanding Follow Up Survey and ORCHESTRA Studies.Journal of medical systems · 2023
   Article
9. Major adverse cardiovascular events (MACE) in patients with severe COVID-19 registered in the ISARIC WHO clinical characterization protocol: A prospective, multinational, observational study.Journal of critical care · 2023
   Observational
10. Thrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry.Research and practice in thrombosis and haemostasis · 2023
    Article
11. Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19.International journal of epidemiology · 2023
    Article
12. Impact of Age and Sex Interaction on Post-Acute Sequelae of COVID-19: An Italian Cohort Study on Adults and Children.Journal of clinical medicine · 2023
    Article
13. Liver injury in hospitalized patients with COVID-19: An International observational cohort study.PloS one · 2023
    Observational
14. Gaps and opportunities in sepsis translational research.EBioMedicine · 2022
    Review
15. TransformEHRs: a flexible methodology for building transparent ETL processes for EHR reuse.Methods of information in medicine · 2022
    Article
16. Symptom-based case definitions for COVID-19: Time and geographical variations for detection at hospital admission among 260,000 patients.Influenza and other respiratory viruses · 2022
    Article
17. An international observational study to assess the impact of the Omicron variant emergence on the clinical epidemiology of COVID-19 in hospitalised patients.eLife · 2022
    Observational
18. Monkeypox: how will we know if the treatments work?The Lancet. Infectious diseases · 2022
    Article
19. ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19.Scientific data · 2022
    Article
20. Global challenges in preparedness and response to epidemic infectious diseases.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Review

Corrections and comments

• Erratum issued
  Correction to Lancet Infect Dis 2021; published online Oct 4, https://doi.org/10.1016/S1473-3099(21)00565-X.2021

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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