Evidence map›Paper›PMID 34618666›Full record

ArticleMicrobiology (Reading, England)2021

The MpsB protein contributes to both the toxicity and immune evasion capacity of

Edward J A Douglas, Seána Duggan, Tarcisio Brignoli, Ruth C Massey

Open access · hybridAbstract read
In one paragraph

Article in Microbiology (Reading, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Metabolic reprogramming promotesMicrobiology (Reading, England) · 2026
    Article
  2. Review
  3. Article
  4. Formation of COBiofilm · 2025
    Article
  5. Article
  6. Extensive re-modelling of the cell wall during the development ofbioRxiv : the preprint server for biology · 2023
    Article
  7. Review
  8. Article
  9. Microbial Musings - November 2021.Microbiology (Reading, England) · 2022
    Article
  10. Microbial Musings - October 2021.Microbiology (Reading, England) · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Edward J A DouglasSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, BS8 1TD, UK.
Seána DugganSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, BS8 1TD, UK.
Tarcisio BrignoliSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, BS8 1TD, UK.
Ruth C MasseySchool of Cellular and Molecular Medicine, University of Bristol, Bristol, BS8 1TD, UK.
University of Bristol · GBUniversity College Cork · IE

Funding

Biotechnology and Biological Sciences Research CouncilWellcome Trust 212258/Z/18/Z
6 · The paper itself

Abstract

Understanding the role specific bacterial factors play in the development of severe disease in humans is critical if new approaches to tackle such infections are to be developed. In this study we focus on genes we have found to be associated with patient outcome following bacteraemia caused by the major human pathogen

Indexed as

Immune EvasionAnti-Bacterial AgentsBacteremiaBacterial ProteinsBacterial ToxinsDrug Resistance, BacterialHumansMembrane PotentialsMutationQuorum SensingStaphylococcal InfectionsStaphylococcus aureusAnti-Bacterial AgentsBacterial ProteinsBacterial ToxinsmpsBserum survivalsmall colony variantsStaphylococcus aureus

Identifiers

PMID34618666
PMCPMC8698210
OpenAlexW3202034035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.