Evidence map›Paper›PMID 34618509›Full record

ArticleRehabilitation psychology2021

Association of physical and mental symptoms with cognition in people with spinal cord injury.

Noelle E Carlozzi, Christopher M Graves, Jonathan P Troost, Dawn M Ehde, Jennifer A Miner, Anna L Kratz

Abstract read
In one paragraph

Article in Rehabilitation psychology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Noelle E CarlozziDepartment of Physical Medicine and Rehabilitation.ORCID 0000-0003-0439-9429
Christopher M GravesDepartment of Physical Medicine and Rehabilitation.
Jonathan P TroostMichigan Institute for Clinical and Health Research.ORCID 0000-0002-1183-8330
Dawn M EhdeDepartment of Rehabilitation Medicine.ORCID 0000-0002-9555-2347
Jennifer A MinerDepartment of Physical Medicine and Rehabilitation.ORCID 0000-0003-2722-1121
Anna L KratzDepartment of Physical Medicine and Rehabilitation.

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Craig H. Neilsen FoundationNational Center for Advancing Translational Sciences (NCATS)NCATS NIH HHS UL1 TR002240
6 · The paper itself

Abstract

PURPOSE/

objectiveTo examine the association between physical and mental symptoms and cognition in people with spinal cord injury. Research Method/Design: One hundred seventy-four community-dwelling adults with spinal cord injury completed several self-reported measures of health-related quality of life (Patient-Reported Outcomes Measurement Information System [PROMIS] Cognitive Abilities, Anxiety, Depression, Fatigue, and Pain Intensity) as well as a traditional neuropsychological assessment (six tests that included assessments of processing speed, working memory, memory, executive function, and attention). A series of multivariable linear regressions were used to test for associations between physical and mental symptoms and the seven ratings of cognition (i.e., scores on PROMIS Cognitive Abilities, as well as the six scores from the neuropsychological tests) after controlling for age, gender, education, and injury classification.

resultsThere was generally no association between symptom measures and neuropsychological test performance with one exception: Greater pain was associated with poorer performance on attention. However, anxiety and fatigue were associated with lower self-perceived cognitive function. Among those individuals with evidence of cognitive impairment in at least one cognitive domain, anxiety was also associated with lower working memory score, and fatigue was associated with lower delayed memory performance. CONCLUSIONS/IMPLICATIONS: While the associations between pain and cognitive performance are consistent with general literature, the absence of a relationship between other symptoms (i.e., depression and fatigue) and cognitive performance was somewhat more surprising. Similarly, the associations between anxiety and fatigue with perceived cognitive function are consistent with the general literature, yet the absence of a relationship with depression was somewhat more surprising. Future work is needed to replicate these findings. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Indexed as

Quality of LifeSpinal Cord InjuriesAdultAnxietyCognitionDepressionHumansNeuropsychological Tests

Identifiers

PMID34618509
PMCPMC8648971

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.