Evidence map›Paper›PMID 34618502›Full record

ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2021

Lifetime and perceived stress, social support, loneliness, and health in autistic adults.

Rachel L Moseley, Julie M Turner-Cobb, Chandler M Spahr, Grant S Shields, George M Slavich

Open access · greenAbstract read
In one paragraph

Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Article
  7. Substance Use Disorder Outcomes and Treatment by Autism Status in Medicaid Enrollees With Substance Use Disorder.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  8. Article
  9. Article
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  12. Traumatic Experiences, Psychological Distress and Suicide-Related Behaviors in Autistic Adults.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  13. Review
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  18. Review
  19. Article
  20. Prospective Memory Performance of Autistic Adults in Everyday Life: The Role of Stress and Motivation.Autism research : official journal of the International Society for Autism Research · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rachel L MoseleyDepartment of Psychology.ORCID 0000-0002-5985-6175
Julie M Turner-CobbDepartment of Psychology.ORCID 0000-0002-3286-3244
Chandler M SpahrDepartment of Psychology.
Grant S ShieldsDepartment of Psychological Science.ORCID 0000-0002-0827-4669
George M SlavichCousins Center for Psychoneuroimmunology.ORCID 0000-0001-5710-3818
Institute of Neuroimmunology of the Slovak Academy of Sciences · SK

Funding

Neural, Inflammatory, and Genomic Mechanisms Underlying Risk for Depression in AdolescenceK08MH103443 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SLAVICH, GEORGE MICHAEL · 2015 to 2018
$772k
NIMH NIH HHS K08 MH103443
6 · The paper itself

Abstract

objectivesAlthough the health consequences of life stress exposure in the general population are well known, how different stressors occurring over the lifetime cause morbidity and mortality in autism is unclear, as are the factors that moderate and mediate these associations. The few studies that have compared autistic and nonautistic individuals have used instruments that yield few stress exposure indices and assess stressors occurring over short time periods.

methodTo address these issues, we used the Stress and Adversity Inventory to assess lifetime stressor exposure and perceived stressor severity in 127 autistic and 104 nonautistic adults. Moderated mediation analysis examined associations between stressor exposure and physical and mental ill-health with respect to the hypothesized mediating role of stressor perception, and moderation effects of loneliness and social support.

resultsAutistic adults experienced more lifetime stressors and generally perceived stressors as being more severe. Greater perceived stressor severity was related to poorer physical and mental health and to greater loneliness and lower social support for both groups. An additional post hoc analysis of the association between diagnostic status and mental ill-health revealed that loneliness mediated the relation between being autistic and having poorer mental health.

conclusionAutistic individuals experienced more lifetime stressors, and their impact on physical and mental health was mediated by perceived stressor severity. Moreover, loneliness and low social support were associated with greater negative impact of lifetime stress exposure on mental health. Interventions that reduce cognitive-perceptual stress appraisals, and that target loneliness and social support, may help reduce risk for stress-related disease in autistic individuals. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Indexed as

Autistic DisorderAdultHumansLonelinessMental HealthSocial SupportStress, Psychological

Identifiers

PMID34618502
PMCPMC8513810
OpenAlexW3167729395

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.