Evidence map›Paper›PMID 34618490›Full record

ArticleJournal of abnormal psychology2021

Increased inflammation predicts nine-year change in major depressive disorder diagnostic status.

Nur Hani Zainal, Michelle G Newman

Open access · hybridAbstract read
In one paragraph

Article in Journal of abnormal psychology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Inflammatory biomarkers and oral microbiome alterations in depression and anxiety disorders: a systematic review.The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nur Hani ZainalDepartment of Psychology.ORCID 0000-0002-2023-3173
Michelle G NewmanDepartment of Psychology.ORCID 0000-0003-0873-1409

Funding

U19 MIDlife in the United States-Diversity Supplement-WellsU19AG051426 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CAROL D. RYFF · 2016 to 2026
$74.8M
STATISTICS COREP01AG020166 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI RYFF, CAROL D. · 2002 to 2015
$50.6M
Harnessing Mobile Technology to Reduce Mental Health Disorders in College PopulationsR01MH115128 · NIMH · WASHINGTON UNIVERSITY · PI EISENBERG, DANIEL, NEWMAN, MICHELLE G · 2018 to 2022
$4.1M
NIA NIH HHS P01 AG020166NIA NIH HHS U19 AG051426NIMH NIH HHS R01 MH115128
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Major Depressive DisorderAdultAgedAged, 80 and overBiomarkersC-Reactive ProteinCross-Sectional StudiesFemaleHumansInflammationInterleukin-6MaleMiddle AgedBiomarkersC-Reactive ProteinIL6 protein, humanInterleukin-6

Identifiers

PMID34618490
PMCPMC8629837
OpenAlexW3202943151

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.