Evidence map›Paper›PMID 34618402›Full record

ArticleMolecular nutrition & food research2021

Effect of Reversal of Whey-Protein to Casein Ratio of Cow Milk, on Insulin, Incretin, and Amino Acid Responses in Humans.

Alessandro Toffolon, Maurizio de Rocco-Ponce, Monica Vettore, Elisabetta Iori, Anna Lante, Paolo Tessari

Open access · hybridAbstract read
In one paragraph

Article in Molecular nutrition & food research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Insights and Perspectives on Plant-Based Beverages.Plants (Basel, Switzerland) · 2023
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alessandro ToffolonDiabetes and Metabolism Division, Department of Medicine (DIMED), University of Padova, Padova, 35128, Italy.
Maurizio de Rocco-PonceDiabetes and Metabolism Division, Department of Medicine (DIMED), University of Padova, Padova, 35128, Italy.
Monica VettoreDiabetes and Metabolism Division, Department of Medicine (DIMED), University of Padova, Padova, 35128, Italy.
Elisabetta IoriDiabetes and Metabolism Division, Department of Medicine (DIMED), University of Padova, Padova, 35128, Italy.
Anna LanteDepartment of Agronomy, Food Natural Resources, Animals & Environment (DAFNAE), University of Padova, Padova, 35123, Italy.
Paolo TessariDiabetes and Metabolism Division, Department of Medicine (DIMED), University of Padova, Padova, 35128, Italy.ORCID 0000-0002-4570-9238
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

scopeMilk-proteins, besides lactose, stimulate insulin and incretin secretion. Although whey-proteins (WP) are more efficient than casein (Cas) in hormone secretion, the effects of reversal of the (WP/Cas) ratio in whole-milk are poorly known. METHODS AND

resultsHealthy volunteers received two different cow-milk drinks, at identical lactose (0.36 g × kg

conclusionsReversal of the (WP/Cas) ratio in cow-milk enhanced the insulin response, an effect possibly mediated by incretins and/or amino acids(s). These data may be useful in designing specific milk formulas with different effects on insulin and incretin response(s).

Indexed as

CaseinsIncretinsAmino AcidsAnimalsBlood GlucoseCattleFemaleGastric Inhibitory PolypeptideHumansInsulinMilkWheyWhey ProteinsAmino AcidsBlood GlucoseCaseinsGastric Inhibitory PolypeptideIncretinsInsulinWhey Proteinsbranched-chain amino acidsC-peptideexperimental milkglucagon-like-polypeptideglucose-inhibitory polypeptide

Identifiers

PMID34618402
PMCPMC9286575
OpenAlexW3203824607

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.