Evidence map›Paper›PMID 34618361›Full record

ArticleCancer2022

The impact of COVID-19 pandemic on access to treatment for children with cancer in India and treating center practices.

Jyotsna Sharma, Amita Mahajan, Sameer Bakhshi, Veerendra Patil, Nishant Verma, Venkatraman Radhakrishnan, Amitabh Singh, Smita Kayal, Rachna Seth, Deepam Pushpam and 1 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Jyotsna SharmaCankids Kidscan, New Delhi, India.
Amita MahajanIndraprastha Apollo Hospital, New Delhi, India.
Sameer BakhshiAll India Institute of Medical Sciences, New Delhi, India.ORCID 0000-0001-9367-4407
Veerendra PatilBasavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.
Nishant VermaKing George's Medical University, Lucknow, India.ORCID 0000-0002-8997-1801
Venkatraman RadhakrishnanCancer Institute, Adyar, India.ORCID 0000-0002-7557-5816
Amitabh SinghVardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Smita KayalJawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Rachna SethAll India Institute of Medical Sciences, New Delhi, India.
Deepam PushpamAll India Institute of Medical Sciences, New Delhi, India.ORCID 0000-0001-8222-331X
Ramandeep Singh AroraMax Super Speciality Hospital Saket, New Delhi, India.ORCID 0000-0002-2613-4539
All India Institute of Medical Sciences · INBasavatarakam Indo American Cancer Hospital and Research Institute · INCancer Institute (WIA) · INCanKids KidsCan · INIndraprastha Apollo Hospitals · INJawaharlal Institute of Post Graduate Medical Education and Research · INKing George's Medical University · INMax Super Speciality Hospital · INVardhman Mahavir Medical College & Safdarjung Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe coronavirus disease 2019 (COVID-19) pandemic led the Indian government to announce a nationwide lockdown on March 23, 2020. This study aimed to explore the impact of the pandemic on the accessibility of care for children with cancer and to view strategies adopted by hospitals for service delivery.

methodsWeekly average of childhood cancer (≤18 years) patient registrations during pre-lockdown period (January 1 to March 23, 2020) were compared with post-lockdown period (March 24 to May 31, 2020). The effect on the scheduled treatment was investigated for post-lockdown period. A survey of health care providers was conducted to determine centers' adopted strategies.

resultsIn 30 participating centers, 1146 patients with childhood cancer (797 pre-lockdown period and 349 post-lockdown period) were registered. The weekly average registration was 67.3 and 35.5 patients during pre-lockdown and post-lockdown respectively (decline of 47.9%). Although most centers experienced this decline, there were 4 that saw an increase in patient registrations. The distribution of patients registered post-lockdown was found significantly different by age (lesser older age, P = .010) and distance (lesser travel distance, P = .001). 36.1% of patients, who were scheduled for any of the treatment modalities (chemotherapy, surgery, radiotherapy, and hematopoietic stem cell transplantation) during the post-lockdown period, experienced delays. Centers adopted several strategies including modifications to treatment protocols, increased use of growth factors, and increased support from social organizations.

conclusionsThis multicenter study from India suggests that the COVID-19 pandemic and the lockdown impacted 2 out of 3 children with cancer. The effect of this on survival is yet to be established.

Indexed as

COVID-19NeoplasmsAgedCommunicable Disease ControlHealth Services AccessibilityHumansIndiaPandemicsSARS-CoV-2childhood cancercoronavirus 2019COVID-19hospital registrationimpactIndia

Identifiers

PMID34618361
PMCPMC8653392
OpenAlexW3204132436

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.