Evidence map›Paper›PMID 34618292›Full record

SynthesisSleep & breathing = Schlaf & Atmung2022

Sleep duration and risk of hyperlipidemia: a systematic review and meta-analysis of prospective studies.

Jinjia Zhang, Jinxin Zhang, Huadong Wu, Rongying Wang

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06420817 (Effect of a Customised Lifestyle Medicine Strategy on Lowering Blood Lipid Levels in Indian Physicians), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06420817 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Effect of a Customised Lifestyle Medicine Strategy on Lowering Blood Lipid Levels in Indian Physicians

TypeinterventionalSponsorJubilee Mission Medical College and Research InstituteRan2024 to 2024Enrolled50ConditionsLifestyle Risk Reduction, Cholesterol, Elevated, LDL Hyperlipoproteinemia, HypertensionArmsIndian version of a 'Portfolio' diet, Physical Activity, Intermittent fasting, Monitoring of sleep and stress levels
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Sleep disorders as risk factors for calcific aortic stenosis.American journal of preventive cardiology · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Observational
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jinjia ZhangDepartment of General Practice, Second Hospital of Hebei Medical University, Heping Western Road No. 215, Shijiazhuang, 050000, Hebei, China.
Jinxin ZhangDepartment of Neurology, Weixian People's Hospital, Weixian, Xingtai, 054700, Hebei, China.
Huadong WuDepartment of Gastrointestinal Surgery, Second Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China.
Rongying WangDepartment of General Practice, Second Hospital of Hebei Medical University, Heping Western Road No. 215, Shijiazhuang, 050000, Hebei, China. wangrongying2017@sina.com.
Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCurrent studies indicate that the association between sleep duration and risk of hyperlipidemia is uncertain. This systematic review aimed to evaluate relevant prospective studies and make a definite conclusion.

methodsThree databases were searched for prospective studies on the relationship between sleep duration and hyperlipidemia risk from their inception to October 2020.

resultsWe identified twelve studies involving 114,439 participants. Follow-up for incident hyperlipidemia ranged from 200 days to 10 years. Neither long (RR:1.00, 95%CI:0.90-1.11, P > 0.05) nor short (RR:0.99, 95%CI:0.94-1.05, P > 0.05) sleep duration had a significant association with increased hyperlipidemia risk in adults. However, long sleep duration was decidedly associated with low HDL-C (RR:0.19, 95%CI: - 0.03-0.40, P < 0.05) and high triglycerides (RR: - 0.20, 95%CI: - 0.43-0.03, P < 0.05) in children and adolescents.

conclusionLong sleep duration has strong associations with risks of low HDL-C and high triglycerides in children and adolescents. The mechanisms underlying this association deserves to be explored in future studies.

Indexed as

HyperlipidemiasSleep Wake DisordersAdolescentAdultChildHumansProspective StudiesSleepTriglyceridesTriglyceridesHyperlipidemiaMeta-analysisRiskSleep duration

Identifiers

PMID34618292
OpenAlexW3201705494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.