Evidence map›Paper›PMID 34618286›Full record

ArticleInternational ophthalmology2022

Interocular asymmetry in distribution of leaks in central serous chorioretinopathy.

Dmitrii S Maltsev, Alexei N Kulikov, Niroj Kumar Sahoo, Filippo Tatti, Alexander S Vasiliev, Maria A Burnasheva, Claudio Iovino, Enrico Peiretti, Jay Chhablani

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in International ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Dmitrii S MaltsevDepartment of Ophthalmology, Military Medical Academy, 21, Botkinskaya str., St. Petersburg, 194044, Russia. glaz.med@yandex.ru.ORCID http://orcid.org/0000-0001-6598-3982
Alexei N KulikovDepartment of Ophthalmology, Military Medical Academy, 21, Botkinskaya str., St. Petersburg, 194044, Russia.
Niroj Kumar SahooSmt. Kanuri Santhamma Centre for Vitreo-Retinal Diseases, L V Prasad Eye Institute, Hyderabad, 34, India.
Filippo TattiDepartment of Surgical Sciences, Eye Clinic, University of Cagliari, Via Ospedale 48, 09124, Cagliari, Italy.
Alexander S VasilievDepartment of Ophthalmology, Military Medical Academy, 21, Botkinskaya str., St. Petersburg, 194044, Russia.
Maria A BurnashevaDepartment of Ophthalmology, Military Medical Academy, 21, Botkinskaya str., St. Petersburg, 194044, Russia.
Claudio IovinoMultidisciplinary Department of Medical, Surgical and Dental Sciences, Eye Clinic, University of Campania Luigi Vanvitelli, Naples, Italy.
Enrico PeirettiDepartment of Surgical Sciences, Eye Clinic, University of Cagliari, Via Ospedale 48, 09124, Cagliari, Italy.
Jay ChhablaniUniversity of Pittsburgh, UPMC Eye Center, 203 Lothrop Street, Pittsburgh, PA, 15213, USA.
S. M. Kirov Military Medical Academy · RUUniversity of Cagliari · ITL V Prasad Eye Institute · INUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study interocular asymmetry in distribution of leaks in central serous chorioretinopathy (CSC). MATERIAL AND

methodsPatients with unilateral CSC were included in this retrospective multicenter study. All patients received multimodal imaging. The prevalence of leaks within 1 disk diameter (DD) peripapillary area and the mean shortest distance between a leak and the optic disk edge was analyzed for the right and left eyes separately based on FA images. Clinical and morphological characteristics were collected and compared between eyes with a peripapillary leak and eyes with a leak elsewhere.

resultsIn total, 152 eyes (77 right eyes and 75 left eyes) of 152 patients (128 males and 24 females) with a mean age of 45.2 ± 9.8 years were included. The mean distance from the leak to the edge of the optic disk was statistically significantly lower (p = 0.0003), and the prevalence of the leaks within the 1 DD-peripapillary area was higher in the left eye than in the right eye (32.1% versus 10.7%, respectively, p = 0.0017). The eyes with a peripapillary leak had a longer duration of the disease (p < 0.05), a wider area of retinal pigment epithelium alteration (p < 0.001), and a higher prevalence of outer retinal atrophy (p < 0.001) compared to the eyes with a leak elsewhere.

conclusionThe left eye showed closer location of the leak to the optic disk edge and higher prevalence of leaks within the peripapillary area. The cases with peripapillary leak commonly demonstrated characteristics of chronic CSC despite relative preservation of visual acuity.

Indexed as

Central Serous ChorioretinopathyAdultChoroidFemaleFluorescein AngiographyHumansMaleMiddle AgedRetrospective StudiesTomography, Optical CoherenceCentral serous chorioretinopathyFluorescent angiographyFundus autofluorescenceOptical coherence tomographyOptical coherence tomography angiography

Identifiers

PMID34618286
OpenAlexW3202739502

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.