Evidence map›Paper›PMID 34618250›Full record

ArticleNeurosurgical review2022

Syndrome of the trephined: clinical spectrum, risk factors, and impact of cranioplasty on neurologic recovery in a prospective cohort.

Lukas Sveikata, Lana Vasung, Amir El Rahal, Andrea Bartoli, Martin Bretzner, Karl Schaller, Armin Schnider, Béatrice Leemann

Abstract read
In one paragraph

Article in Neurosurgical review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  5. Article
  6. Review
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  8. Article
  9. Review
  10. Skull defect - Frontotemporal dementia sagging brain syndrome.Annals of clinical and translational neurology · 2025
    Article
  11. Article
  12. Functional outcome after late cranioplasty after decompressive craniectomy: a single-center retrospective study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lukas SveikataDivision of Neurorehabilitation, Department of Clinical Neurosciences, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva, Switzerland. lsveikata@mgh.harvard.edu.ORCID http://orcid.org/0000-0001-8015-7929
Lana VasungBoston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Amir El RahalDivision of Neurosurgery, Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland.
Andrea BartoliDivision of Neurosurgery, Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland.
Martin BretznerJ. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Karl SchallerDivision of Neurosurgery, Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland.
Armin SchniderDivision of Neurorehabilitation, Department of Clinical Neurosciences, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Béatrice LeemannDivision of Neurorehabilitation, Department of Clinical Neurosciences, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

Funding

nccr - on the move P2GEP3_191584
6 · The paper itself

Abstract

Syndrome of the trephined (SoT) is an underrecognized complication after decompressive craniectomy. We aimed to investigate SoT incidence, clinical spectrum, risk factors, and the impact of the cranioplasty on neurologic recovery. Patients undergoing a large craniectomy (> 80 cm

Indexed as

Decompressive CraniectomyPlastic Surgery ProceduresHumansPostoperative ComplicationsProspective StudiesRetrospective StudiesRisk FactorsSkullCranioplastyDecompressive craniectomyMotor trephine syndromeNeurologic recoveryPostoperative complicationsRehabilitationSinking skin flapStrokeSyndrome of the trephined

Identifiers

PMID34618250
PMCPMC8976790

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.