Evidence map›Paper›PMID 34618193›Full record

ArticleInternational urogynecology journal2022

Online prediction tool for female pelvic floor dysfunction: development and validation.

Zhuoran Chen, Susana Mustafa Mikhail, Melissa Buttini, Alex Mowat, Gunter Hartel, Christopher Maher

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In one paragraph

Article in International urogynecology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Zhuoran ChenRoyal Brisbane Women's Hospital, Department of Obstetrics and Gynaecology, Women's and Newborn Services, NHB Level 5, Butterfield Street, Herston, Brisbane, QLD, 4029, Australia. zhuoran.chen@unsw.edu.au.ORCID 0000-0002-3974-3632
Susana Mustafa MikhailRoyal Brisbane Women's Hospital, Department of Obstetrics and Gynaecology, Women's and Newborn Services, NHB Level 5, Butterfield Street, Herston, Brisbane, QLD, 4029, Australia.
Melissa ButtiniThe Wesley Hospital, Auchenflower, Brisbane, QLD, Australia.
Alex MowatUniversity of Queensland, Queen Elizabeth II Hospital, Greenslopes, Brisbane, QLD, Australia.
Gunter HartelQIMR Berghofer Medical Research Institute, Statistics Unit, Herston, QLD, Australia.
Christopher MaherRoyal Brisbane Women's Hospital, Department of Obstetrics and Gynaecology, Women's and Newborn Services, NHB Level 5, Butterfield Street, Herston, Brisbane, QLD, 4029, Australia.
Royal Brisbane and Women's Hospital · AUThe University of Queensland · AUQIMR Berghofer Medical Research Institute · AUWesley Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisThe aim was to develop and validate (internally and externally) a prediction model for the presence and diagnosis of pelvic floor dysfunction (PFD) in women, including pelvic organ prolapse, stress urinary incontinence and/or overactive bladder via a patient-completed online tool.

methodsUsing a retrospective cohort of women aged >18 years, from multiple tertiary gynaecology units within Queensland, Australia (2014-2018), the prediction model was developed via penalized logistic regression with internal and external validation utilizing multiple clinical predictors (42 questions from the Australian Pelvic Floor Questionnaire and demographics: age, body mass index, parity and mode of delivery). The main outcome measures were the accuracy of the model in predicting a diagnosis of pelvic floor dysfunction and its specific conditions of prolapse and incontinence.

resultsA total of 3,501 women were utilized for model development and internal validation and 449 for external validation. On internal validation the model correctly identified those with PFD with 97% sensitivity, 74% specificity and a concordance index (C-index) of 0.96. Predictions of pelvic organ prolapse were also accurate, with 86% sensitivity, 83% specificity, C-index 0.83, as was stress urinary incontinence, 84% sensitivity, 87% specificity, C-index 0.87, and overactive bladder, 76% sensitivity, 77% specificity, C-index 0.77. External validation confirmed the model's accuracy with a similar C-index in all parameters.

conclusionsThis model provides an accurate online tool to differentiate between those with and without PFD and diagnoses of common pelvic floor disorders. It serves as a valuable self-assessment for women and primary care providers.

Indexed as

Fecal IncontinencePelvic Floor DisordersPelvic Organ ProlapseUrinary Bladder, OveractiveUrinary Incontinence, StressAustraliaFemaleHumansPelvic FloorPregnancyRetrospective StudiesSurveys and QuestionnairesOnline toolPrediction modelProlapseUrinary incontinence

Identifiers

PMID34618193
OpenAlexW3204442176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.