Evidence map›Paper›PMID 34618178›Full record

ArticleDiabetologia2022

Association of birthweight and penetrance of diabetes in individuals with HNF4A-MODY: a cohort study.

Jonathan M Locke, Petra Dusatkova, Kevin Colclough, Alice E Hughes, John M Dennis, Beverley Shields, Sarah E Flanagan, Maggie H Shepherd, Emma L Dempster, Andrew T Hattersley and 3 more

Open access · hybridAbstract readLetter
In one paragraph

Article in Diabetologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Diabetes mellitusFrontiers in endocrinology · 2025
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Jonathan M LockeInstitute of Biomedical & Clinical Science, College of Medicine & Health, University of Exeter, Exeter, UK. j.locke@exeter.ac.uk.ORCID 0000-0001-9516-5251
Petra DusatkovaDepartment of Pediatrics, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.ORCID 0000-0002-8647-9088
Kevin ColcloughExeter Genomics Laboratory, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.ORCID 0000-0003-0566-4853
Alice E HughesInstitute of Biomedical & Clinical Science, College of Medicine & Health, University of Exeter, Exeter, UK.ORCID 0000-0003-1352-4447
John M DennisInstitute of Biomedical & Clinical Science, College of Medicine & Health, University of Exeter, Exeter, UK.ORCID 0000-0002-7171-732X
Beverley ShieldsInstitute of Biomedical & Clinical Science, College of Medicine & Health, University of Exeter, Exeter, UK.ORCID 0000-0003-3785-327X
Sarah E FlanaganInstitute of Biomedical & Clinical Science, College of Medicine & Health, University of Exeter, Exeter, UK.ORCID 0000-0002-8670-6340
Maggie H ShepherdInstitute of Biomedical & Clinical Science, College of Medicine & Health, University of Exeter, Exeter, UK.ORCID 0000-0003-2660-0955
Emma L DempsterInstitute of Biomedical & Clinical Science, College of Medicine & Health, University of Exeter, Exeter, UK.ORCID 0000-0003-1257-5314
Andrew T HattersleyInstitute of Biomedical & Clinical Science, College of Medicine & Health, University of Exeter, Exeter, UK.ORCID 0000-0001-5620-473X
Michael N WeedonInstitute of Biomedical & Clinical Science, College of Medicine & Health, University of Exeter, Exeter, UK.ORCID 0000-0002-6174-6135
Stepanka PruhovaDepartment of Pediatrics, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.ORCID 0000-0001-8019-8026
Kashyap A PatelInstitute of Biomedical & Clinical Science, College of Medicine & Health, University of Exeter, Exeter, UK. k.a.patel@exeter.ac.uk.ORCID 0000-0002-9240-8104
University of Exeter · GBCharles University · CZRoyal Devon & Exeter NHS Foundation Trust · GB

Funding

Department of HealthWellcome Trust 105636Wellcome Trust 219606
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 2Birth WeightCohort StudiesHepatocyte Nuclear Factor 1-alphaHepatocyte Nuclear Factor 4HumansMutationPenetranceHepatocyte Nuclear Factor 1-alphaHepatocyte Nuclear Factor 4HNF4A protein, humanBirthweightHepatocyte nuclear factor-4 alpha (HNF4A)Maturity-onset diabetes of the young (MODY)Penetrance

Identifiers

PMID34618178
PMCPMC8660751
OpenAlexW3203762998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.