ArticlePlant physiology2021
B-box protein BBX32 integrates light and brassinosteroid signals to inhibit cotyledon opening.
Article in Plant physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Antagonistic regulation of PIF4 and HY5 activity by BBX28 regulates thermomorphogenesis.Science advances · 2026Article
- The VvBZR1-VvHY5 Module Integrates Brassinosteroid and Light Signaling to Regulate Anthocyanin Biosynthesis in Grape.Plant, cell & environment · 2026Article
- Multifaceted roles of BBX transcription factors: impacts on key agronomical traits and environmental resilience.The New phytologist · 2026Review
- Genome-wide analysis of PfBBXs transcription factors in Perilla frutescens and their expression responses to different light intensities.Plant molecular biology · 2025Article
- Light Quantity Impacts Early Response to Cold and Cold Acclimation in Young Leaves of Arabidopsis.Plant, cell & environment · 2025Article
- The BBX family and their response to abiotic stress in ginger (Zingiber officinale Roscoe).BMC genomics · 2025Article
- BTB/POZ-MATH proteins regulate Arabidopsis seedling development by promoting auxin-independent degradation of the Aux/IAA protein IAA10.Plant physiology · 2025Article
- Interaction of the Transcription Factors BES1/BZR1 in Plant Growth and Stress Response.International journal of molecular sciences · 2024Review
- Genome-wide analysis of blueberry B-box family genes and identification of members activated by abiotic stress.BMC genomics · 2023Article
- The Abundant and Unique Transcripts and Alternative Splicing of the Artificially Autododecaploid London Plane (International journal of molecular sciences · 2023Article
- Jasmonates regulate apical hook development by repressing brassinosteroid biosynthesis and signaling.Plant physiology · 2023Article
- Tuning the Wavelength: Manipulation of Light Signaling to Control Plant Defense.International journal of molecular sciences · 2023Review
- Multi-layered roles of BBX proteins in plant growth and development.Stress biology · 2023Review
- Review
- SlBBX28 positively regulates plant growth and flower number in an auxin-mediated manner in tomato.Plant molecular biology · 2022Article
- The photomorphogenic repressors BBX28 and BBX29 integrate light and brassinosteroid signaling to inhibit seedling development in Arabidopsis.The Plant cell · 2022Article
- BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signalling.The New phytologist · 2022Article
- Phytochrome interacting factor MdPIF7 modulates anthocyanin biosynthesis and hypocotyl growth in apple.Plant physiology · 2022Article
- Integration of Light and Brassinosteroid Signaling during Seedling Establishment.International journal of molecular sciences · 2021Review
- Here comes the sun: a BBX protein slows cotyledon opening following light exposure.Plant physiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cotyledon opening is a key morphological change that occurs in seedlings during de-etiolation. Brassinosteroids (BRs) inhibit the opening of cotyledons in darkness while light promotes cotyledon opening. The molecular regulation of the interplay between light and BR to regulate cotyledon opening is not well understood. Here, we show the B-box protein BBX32 negatively regulates light signaling and promotes BR signaling to inhibit cotyledon opening in Arabidopsis (Arabidopsis thaliana). BBX32 is highly expressed in the cotyledons of seedlings during de-etiolation. bbx32 and 35S:BBX32 seedlings exhibit enhanced and reduced cotyledon opening, respectively, in response to both light and brassinazole treatment in dark, suggesting that BBX32 mediates cotyledon opening through both light and BR signaling pathways. BBX32 expression is induced by exogenous BR and is upregulated in bzr1-1D (BRASSINAZOLE RESISTANT1-1D). Our in vitro and in vivo interaction studies suggest that BBX32 physically interacts with BZR1. Further, we found that PHYTOCHROME-INTERACTING FACTOR 3 (PIF3) interacts with BBX32 and promotes BR-mediated cotyledon closure. BBX32, BZR1, and PIF3 regulate the expression of common target genes that modulate the opening and closing of cotyledons. Our work suggests BBX32 integrates light and BR signals to regulate cotyledon opening during de-etiolation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.