ArticlePlant physiology2021
OsFes1C, a potential nucleotide exchange factor for OsBiP1, is involved in the ER and salt stress responses.
Article in Plant physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- The Assembly of Alginate-Chitosan-Xanthine Hydrogel andMolecules (Basel, Switzerland) · 2026Article
- GWAS and Regularised Regression Identify SNPs Associated with Candidate Genes for Stage-Specific Salinity Tolerance in Rice.Plants (Basel, Switzerland) · 2026Article
- Cerium-coated FeFrontiers in plant science · 2026Article
- Rice RING E3 Ligase OsRMT1 Negatively Regulates Salt Tolerance by Degrading the Canonical Salt-Responsive Protein OsMBL1.Plant biotechnology journal · 2025Article
- Field-crop transcriptome models are enhanced by measurements in systematically controlled environments.Genome biology · 2025Article
- OsPIPK-FAB, A Negative Regulator in Rice Immunity Unveiled by OsMBL1 Inhibition.Rice (New York, N.Y.) · 2024Article
- Genetic and Physiological Insights into Salt Resistance in Rice through Analysis of Germination, Seedling Traits, and QTL Identification.Life (Basel, Switzerland) · 2024Article
- TaMYB44-5A reduces drought tolerance by repressing transcription of TaRD22-3A in the abscisic acid signaling pathway.Planta · 2024Article
- Article
- Parallel evolution of two AIM24 protein subfamilies and their conserved functions in ER stress tolerance in land plants.Plant communications · 2023Article
- MeJA-mediated enhancement of salt-tolerance of Populus wutunensis by 5-aminolevulinic acid.BMC plant biology · 2023Article
- Editorial: Adaptive evolution of grasses.Frontiers in plant science · 2023Article
- Heat and drought induced transcriptomic changes in barley varieties with contrasting stress response phenotypes.Frontiers in plant science · 2022Article
- Distribution, expression of hexaploid wheatFrontiers in plant science · 2022Article
- Plant Salinity Stress Response and Nano-Enabled Plant Salt Tolerance.Frontiers in plant science · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The endoplasmic reticulum (ER) quality control system monitors protein homeostasis and relies on the activity of many molecular chaperones. Binding immunoglobulin protein (BiP) is a major ER luminal chaperone that is involved in most functions of the organelle. BiP activity is tightly regulated by nucleotide exchange factors (NEFs). However, information about NEFs in plants is limited. We obtained a Fes1-like protein (OsFes1C) through isobaric tags for relative and absolute quantitation-based proteomics analysis of ER-stressed rice (Oryza sativa) seeds. Unlike its homologs in yeast and mammals, which are located in the cytosol and respond to heat stress, OsFes1C is an ER membrane protein and responds to ER and salt stresses. OsFes1C interacts directly with OsBiP1 and the interaction is inhibited by ATP but promoted by ADP, suggesting that OsFes1C acts as a potential NEF of OsBiP1 in vivo. Overexpression or suppression of OsFes1C led to hypersensitivity to ER stress and affected the growth of rice. Furthermore, we established that OsFes1C directly interacts with a putative salt response protein and is involved in the salt response. Taken together, our study marks an important step toward elucidating the functional mechanisms of an identified ER stress response factor in rice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.