ArticlePlant physiology2021
Knock out of transcription factor WRKY53 thickens sclerenchyma cell walls, confers bacterial blight resistance.
Article in Plant physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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40 citing papers in PubMed, 103 citations in OpenAlex.
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- Multiplexed Engineering of Disease Resistance and Lodging Tolerance in Wheat Via a Single Xylan Modifying Glycosyltransferase.Plant biotechnology journal · 2026Article
- Natural variation in WRKY53 confers cold tolerance at the booting stage between japonica and indica rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Loss of function of OsWRKY53-OsARF18-OsRR22 significantly enhances rice salt tolerance.BMC plant biology · 2026Article
- Guardians or Gateways? The Intricate Relationship Between Plant Cell Walls and Pathogenic Xanthomonas.Molecular plant pathology · 2026Review
- WRKY Transcription Factors: Integral Regulators of Defence Responses to Biotic Stress in Crops.Plant biotechnology journal · 2026Review
- OsWRKY53-OsGT1 Module Regulates Rice Tiller Development and Is Involved in Fine-Tuning Strigolactone Signaling.Plant biotechnology journal · 2026Article
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- CmHY5-CmWRKY23/69-Horticulture research · 2026Article
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- Effect of Singlet Oxygen on the Stomatal and Cell Wall of Rice Seedling Under Different Stresses.International journal of molecular sciences · 2025Article
- SlPLT6 controls ripening initiation and quality traits through modulation of histone acetylation and methylation in tomato.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The OsMAPK6-OsWRKY72 module positively regulates rice leaf angle through brassinosteroid signals.Plant communications · 2025Article
- Proteomes and ubiquitylomes reveal the regulation mechanism of cold tolerance mediated byFrontiers in plant science · 2025Article
- Strategies utilized by plants to defend againstFrontiers in plant science · 2025Review
- Combined transcriptome and metabolome analysis ofFrontiers in plant science · 2025Article
- The root cortex of the Poaceae: a diverse, dynamic, and dispensable tissue.Plant and soil · 2025Review
- Identification and Genome Sequencing of Novel Virulent Strains ofPathogens (Basel, Switzerland) · 2024Article
- OsWRKY70 Plays Opposite Roles in Blast Resistance and Cold Stress Tolerance in Rice.Rice (New York, N.Y.) · 2024Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant cell walls are the first physical barrier against pathogen invasion, and plants thicken the cell wall to strengthen it and restrain pathogen infection. Bacterial blight is a devastating rice (Oryza sativa) disease caused by Xanthomonas oryzae pv. oryzae (Xoo), which typically enters the rice leaf through hydathodes and spreads throughout the plant via the xylem. Xoo interacts with cells surrounding the xylem vessel of a vascular bundle, but whether rice strengthens the sclerenchyma cell walls to stop pathogen proliferation is unclear. Here, we found that a WRKY protein, OsWRKY53, negatively confers resistance to Xoo by strengthening the sclerenchyma cell walls of the vascular bundle. OsMYB63 acts as a transcriptional activator and promotes the expression of three secondary cell wall-related cellulose synthase genes to boost cellulose accumulation, resulting in thickened sclerenchyma cell walls. Both OsWRKY53 and OsMYB63 are abundantly expressed in sclerenchyma cells of leaf vascular bundles. OsWRKY53 functions as a transcriptional repressor and acts genetically upstream of OsMYB63 to suppress its expression. The OsWRKY53-overexpressing and OsMYB63 knockout plants had thinner sclerenchyma cell walls, showing susceptibility to Xoo, while the OsWRKY53 knockout and OsMYB63-overexpressing plants had thicker sclerenchyma cell walls, exhibiting resistance to Xoo. These results suggest that modifying these candidate genes provides a strategy to improve rice resistance to bacterial pathogens.
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