Evidence map›Paper›PMID 34617682›Full record

ArticleJournal of diabetes2022

Pregnancy outcomes in women with type 1 diabetes in China during 2004 to 2014: A retrospective study (the CARNATION Study).

Sihui Luo, Xingwu Ran, Mei Zhang, Ji Hu, Daizhi Yang, Dalong Zhu, Jiajun Zhao, Xinhua Xiao, Xiaohui Guo, Tao Yang and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Sihui Luo *Department of Endocrinology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.ORCID https://orcid.org/0000-0001-8503-0310
Xingwu Ran *Department of Endocrinology and Metabolism, West China University Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-6634-1241
Mei Zhang *Department of Endocrinology and Metabolism, Jiangsu Province Hospital, Nanjing, China.
Ji Hu *Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Daizhi YangDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Dalong ZhuDepartment of Endocrinology and Metabolism, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.ORCID https://orcid.org/0000-0001-5775-5103
Jiajun ZhaoDepartment of Endocrinology and Metabolism, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.ORCID https://orcid.org/0000-0003-3267-9292
Xinhua XiaoDepartment of Endocrinology and Metabolism, Peking Union Medical College Hospital, Beijing, China.
Xiaohui GuoDepartment of Endocrinology and Metabolism, Peking University First Hospital, Beijing, China.
Tao YangDepartment of Endocrinology and Metabolism, Jiangsu Province Hospital, Nanjing, China.
Qin HuangDepartment of Endocrinology and Metabolism, Changhai Hospital, Second Military Medical University, Shanghai, China.
Fang LiuDepartment of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Lu JingDepartment of Endocrinology and Metabolism, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Jing MaDepartment of Endocrinology and Metabolism, West China University Hospital, Sichuan University, Chengdu, China.
Xinli ZhouDepartment of Endocrinology and Metabolism, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.
Fan PingDepartment of Endocrinology and Metabolism, Peking Union Medical College Hospital, Beijing, China.
Nan GuDepartment of Endocrinology and Metabolism, Peking University First Hospital, Beijing, China.
Wenwen LiDepartment of Endocrinology and Metabolism, Changhai Hospital, Second Military Medical University, Shanghai, China.
Yaling YangDepartment of Endocrinology and Metabolism, The Second Xiangya Hospital of Central South University, Changsha, China.
Chen FangDepartment of Endocrinology and Metabolism, The Second Affiliated Hospital of Soochow University, Suzhou, China.ORCID https://orcid.org/0000-0003-4329-9471
Wei BaoDepartment of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0002-7301-5786
Xueying ZhengDepartment of Endocrinology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Jinhua YanDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Zhiguang ZhouDepartment of Endocrinology and Metabolism, The Second Xiangya Hospital of Central South University, Changsha, China.ORCID https://orcid.org/0000-0002-0374-1838
Jianping WengDepartment of Endocrinology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

Funding

National Health and Family Planning Commission of the People's Republic of China, Foundation for Public Welfare Industry Research Project 201502011
6 · The paper itself

Abstract

backgroundWe aimed to report pregnancy outcomes of women with type 1 diabetes (T1D) in China, on which data were sparse.

methodsThis is a nationwide retrospective study conducted in 11 general medical centers in 8 cities across China. We investigated the clinical data of all women who attended these centers with a singleton pregnancy and whose pregnancy ended between 1 January 2004 and 31 December 2014. Pregnancies of women with pregestational T1D were ascertained and compared with those of women without T1D.

resultsFrom over 300 000 pregnancies over the 11-year study period, we identified 265 singleton pregnancies of women with T1D. One maternal death was documented among 265 (0.37%) women with T1D and 83 among 318 486 (0.03%) women without T1D. Women with T1D suffered from higher rates of pregnancy loss (13.21% vs 2.92%, crude risk ratio [cRR] 5.08 [95% CI, 3.56-7.26]) and preeclampsia (17.74% vs 4.20%, cRR 4.94 [95% CI, 3.60-6.77]) compared with those without T1D. Infants of these women with T1D had elevated rates of neonatal death (5.65% vs 0.16%, cRR 37.36 [95% CI, 21.21-65.82]) and congenital malformation(s) (8.26% vs 3.53%, cRR 2.46 [95% CI, 1.54-3.93]) compared with those of women without T1D. No significant improvement in pregnancy outcomes in women with T1D was observed over the period 2004 to 2014.

conclusionsPregnancy outcomes were persistently poor in women with T1D during 2004 to 2014 in China. Pregnancy care needs to be improved to reduce adverse pregnancy outcomes among Chinese women with T1D.

Indexed as

Diabetes Mellitus, Type 1DianthusPregnancy in DiabeticsFemaleHumansInfantInfant, NewbornPregnancyPregnancy OutcomePrenatal CareRetrospective Studies1型糖尿病diabetes mellitus type 1pregnancy in diabeticspregnancy outcomesretrospective study回顾性研究妊娠结局糖尿病患者妊娠

Identifiers

PMID34617682
PMCPMC9060029

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.