ArticleJVS-vascular science2020
Synchrotron Radiation-based X-ray phase-contrast imaging of the aortic walls in acute aortic dissection.
Article in JVS-vascular science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Structural and transcriptomic alterations underlying the progression of aortic dissection in Fbn1Scientific reports · 2026Article
- The Use of Synchrotron Radiation in the Medical Sciences.Photon science · 2026Article
- Density of fresh wall of acute aortic dissection with synchrotron-based x-ray phase tomography.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- High-Resolution Phase-Contrast Tomography on Human Collagenous Tissues: A Comprehensive Review.Tomography (Ann Arbor, Mich.) · 2023Review
- Preparation of large biological samples for high-resolution, hierarchical, synchrotron phase-contrast tomography with multimodal imaging compatibility.Nature protocols · 2023Review
- Mechanism of sac expansion without evident endoleak analyzed with X ray phase-contrast tomography.JVS-vascular science · 2023Article
- Impact of High-Resolution Epiaortic Ultrasonographic Imaging on Evaluating Aortic Wall Pathology.Annals of vascular diseases · 2022Article
- Great start predicts bright future forJVS-vascular science · 2021Article
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSynchrotron radiation-based X-ray phase-contrast tomography (XPCT) imaging is an innovative modality for the quantitative analysis of three-dimensional morphology. XPCT has been used in this study to evaluate ascending aorta specimens from patients with acute type A aortic dissection (ATAAD) and to analyze the morphologic structure of the aortic wall in patients with this condition.
methodsAortic specimens from 12 patients were obtained during repairs for ATAAD and were fixed with formalin. Five patients had Marfan syndrome (MFS), and seven did not. In addition, six normal aortas were obtained from autopsies. Using XPCT (effective pixel size, 12.5 μm; density resolution, 1 mg/cm
resultsThe density of the TM was almost constant within each normal aorta (mean, 1.081 ± 0.001 g/cm
conclusionsXPCT exhibited differences in the structure of the aortic wall in aortic dissection specimens with and without MFS and in normal aortas. Medial density was homogeneous in the normal aortas, markedly varied in those with MFS, and was significantly lower and different among those without MFS. These changes may be present in the TM before the onset of aortic dissection.
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