ArticleInnovation in aging2021
Age Differences in Multimodal Quantitative Sensory Testing and Associations With Brain Volume.
Article in Innovation in aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
15 citing papers in PubMed.
- Prevention and Treatment of Postsurgical Pain: Pharmacologic and Nonpharmacologic Interventions Across the Surgical Continuum.Clinics in geriatric medicine · 2026Review
- Repeated plantar electrical stimulation is associated with altered lower-limb somatosensory processing in older adults: evidence from somatosensory evoked potentials.Frontiers in aging neuroscience · 2026Article
- Intra- and Inter-examiner Reliability of Quantitative Sensory Testing of Knee Joints in Healthy Subjects.Progress in rehabilitation medicine · 2026Article
- Widespread and prolonged pain may reduce brain clearance capacity only via sleep impairment: Evidence from participants with knee pain.The journal of pain · 2025Article
- Article
- A multi-modal evaluation of experimental pain and psychological function in women with carpometacarpal osteoarthritis.Osteoarthritis and cartilage open · 2024Article
- Aging-associated decrease of PGC-1α promotes pain chronification.Aging cell · 2024Article
- Aging is associated with impaired triggering of TRPV3-mediated cutaneous vasodilation: a crucial process for local heat exposure.GeroScience · 2024Article
- Preliminary Characterization of Age and Chronic Low Back Pain Effects on Multimodal Pain Sensitivity: A Comparison Study in Older Adults with and Without Chronic Low Back Pain.The journal of pain · 2024Article
- Accelerated Brain Aging Mediates the Association Between Psychological Profiles and Clinical Pain in Knee Osteoarthritis.The journal of pain · 2024Article
- Age-associated changes in multimodal pain perception.Age and ageing · 2024Article
- Characterization of the neuropathic pain component contributing to myalgia in patients with myotonic dystrophy type 1 and 2.Frontiers in neurology · 2024Article
- Body composition and body mass index are independently associated with widespread pain and experimental pain sensitivity in older adults: a pilot investigation.Frontiers in pain research (Lausanne, Switzerland) · 2024Article
- Quantitative Sensory Testing Across Chronic Pain Conditions and Use in Special Populations.Frontiers in pain research (Lausanne, Switzerland) · 2021Review
- Clinical and biobehavioral phenotypic assessments and data harmonization for the RE-JOIN research consortium: Recommendations for common data element selection.Neurobiology of pain (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
BACKGROUND AND
objectivesSomatosensory function is critical for successful aging. Prior studies have shown declines in somatosensory function with age; however, this may be affected by testing site, modality, and biobehavioral factors. While somatosensory function declines are associated with peripheral nervous system degradation, little is known regarding correlates with the central nervous system and brain structure in particular. The objectives of this study were to examine age-related declines in somatosensory function using innocuous and noxious stimuli, across 2 anatomical testing sites, with considerations for affect and cognitive function, and associations between somatosensory function and brain structure in older adults. RESEARCH DESIGN AND
methodsA cross-sectional analysis included 84 "younger" (
resultsSignificant age × test site interaction effects were observed for warmth detection ( DISCUSSION AND IMPLICATIONS: Our findings indicate healthy older adults display alterations in sensory responses to innocuous and noxious stimuli compared to younger adults and, furthermore, these alterations are uniquely affected by anatomical site. These findings suggest a nonuniform decline in somatosensation in older adults, which may represent peripheral and central nervous system alterations part of aging processes.
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Registered trials
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