Evidence map›Paper›PMID 34616848›Full record

ArticleBioMed research international2021

Resveratrol Suppresses Annulus Fibrosus Cell Apoptosis through Regulating Oxidative Stress Reaction in an Inflammatory Environment.

Qunqun Shan, Ning Li, Fan Zhang, Peng Yu, Qingxi Meng

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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  5. The MnOGels (Basel, Switzerland) · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Qunqun ShanDepartment of Orthopedics, The 960 Hospital of PLA, Jinan, Shandong, China.
Ning LiWeifang People's Hospital, Weifang, Shandong, China.
Fan ZhangDepartment of Orthopedics, Eightieth Group Army Hospital of PLA Army, Weifang, Shandong, China.
Peng YuThe 11th Cadre Rest Center of Shandong Military Region, Jinan, Shandong, China.
Qingxi MengDepartment of Orthopedics, The 960 Hospital of PLA, Jinan, Shandong, China.ORCID https://orcid.org/0000-0003-3684-9578
People's Liberation Army 401 Hospital · CNWeifang People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During disc degeneration, the increase of inflammatory cytokines and decrease of disc cell density are two prominent features. Enhanced inflammatory reaction contributes to disc annulus fibrosus (AF) cell apoptosis. In this study, we investigated whether resveratrol can suppress AF cell apoptosis in an inflammatory environment. Rat disc AF cells were cultured in medium with or without tumor necrosis factor-

Indexed as

ApoptosisOxidative StressAnimalsAnnulus FibrosusBiomarkersCaspase 3Caspase 9Gene Expression RegulationInflammationPoly(ADP-ribose) PolymerasesRatsReactive Oxygen SpeciesResveratrolSuperoxide DismutaseBiomarkersCaspase 3Caspase 9Poly(ADP-ribose) PolymerasesReactive Oxygen SpeciesResveratrolSuperoxide Dismutase

Identifiers

PMID34616848
PMCPMC8490034
OpenAlexW3203555658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.