Evidence map›Paper›PMID 34616744›Full record

ReviewFrontiers in cell and developmental biology2021

Fundamental Mechanisms of the Cell Death Caused by Nitrosative Stress.

Fulin Wang, Qiuhuan Yuan, Fengying Chen, Jiaojiao Pang, Chang Pan, Feng Xu, Yuguo Chen

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 1 pooled it
18.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 1 synthesis or guideline pooled it, 122 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Intestinal Epithelial-Protective Effects ofJournal of microbiology and biotechnology · 2026
    Article
  4. Article
  5. Article
  6. Antioxidants (Basel, Switzerland) · 2026
    Article
  7. Review
  8. Co-exposure to arsenic and nickel induces oxidative stress and mineral imbalance, impairing male reproductive parameters in Wistar rats.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Contribution of adenosine ATurkish journal of medical sciences · 2026
    Article
  18. Review
  19. Review
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Fulin WangDepartment of Emergency Medicine, Qilu Hospital, Shandong University, Jinan, China.
Qiuhuan YuanDepartment of Emergency Medicine, Qilu Hospital, Shandong University, Jinan, China.
Fengying ChenEmergency Department, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Jiaojiao PangDepartment of Emergency Medicine, Qilu Hospital, Shandong University, Jinan, China.
Chang PanDepartment of Emergency Medicine, Qilu Hospital, Shandong University, Jinan, China.
Feng XuDepartment of Emergency Medicine, Qilu Hospital, Shandong University, Jinan, China.
Yuguo ChenDepartment of Emergency Medicine, Qilu Hospital, Shandong University, Jinan, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNQilu Hospital of Shandong University · CNInner Mongolia Medical University · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitrosative stress, as an important oxygen metabolism disorder, has been shown to be closely associated with cardiovascular diseases, such as myocardial ischemia/reperfusion injury, aortic aneurysm, heart failure, hypertension, and atherosclerosis. Nitrosative stress refers to the joint biochemical reactions of nitric oxide (NO) and superoxide (O

Indexed as

cardiovascular diseasescell deathnitric oxidenitrosative stressperoxynitritereactive nitrogen species

Identifiers

PMID34616744
PMCPMC8488117
OpenAlexW3201268525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.