Evidence map›Paper›PMID 34616691›Full record

ArticleFrontiers in cellular and infection microbiology2021

Analysis of Susceptibility to the Antimicrobial and Anti-Biofilm Activity of Human Milk Lactoferrin in Clinical Strains of

Jacky Lu, Miriam A Guevara, Jamisha D Francis, Sabrina K Spicer, Rebecca E Moore, Schuyler A Chambers, Kelly M Craft, Shannon D Manning, Steven D Townsend, Jennifer A Gaddy

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Matrine AttenuatesMicroorganisms · 2025
    Article
  5. Frontiers in veterinary science · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jacky LuDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States.
Miriam A GuevaraDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States.
Jamisha D FrancisDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States.
Sabrina K SpicerDepartment of Chemistry, Vanderbilt University, Nashville, TN, United States.
Rebecca E MooreDepartment of Chemistry, Vanderbilt University, Nashville, TN, United States.
Schuyler A ChambersDepartment of Chemistry, Vanderbilt University, Nashville, TN, United States.
Kelly M CraftDepartment of Chemistry, Harvard University, Cambridge, MA, United States.
Shannon D ManningDepartment of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI, United States.
Steven D TownsendDepartment of Chemistry, Vanderbilt University, Nashville, TN, United States.
Jennifer A GaddyDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States.
Vanderbilt University · USHarvard University · USMichigan State University · USVanderbilt University Medical Center · US

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Training In Cardiovascular ResearchT32HL007411 · NHLBI · VANDERBILT UNIVERSITY · PI BECKMAN, JOSHUA A · 1985 to 2020
$7.2M
Chemical Biology of Infectious Diseases (CBID) Training ProgramT32AI112541 · NIAID · VANDERBILT UNIVERSITY · PI Eric P Skaar · 2015 to 2026
$4.0M
NCATS NIH HHS UL1 TR000445NCRR NIH HHS UL1 RR024975NHLBI NIH HHS T32 HL007411NIAID NIH HHS T32 AI112541
6 · The paper itself

Abstract

Group B

Indexed as

Streptococcal InfectionsStreptococcus agalactiaeAnti-Bacterial AgentsBiofilmsFemaleHumansInfant, NewbornLactoferrinMilk, HumanPregnancyAnti-Bacterial AgentsLactoferrinantimicrobialbiofilmlactoferrinnutritional immunityStreptococcus agalactiae

Identifiers

PMID34616691
PMCPMC8488155
OpenAlexW3200453308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.